Cloning and transcription regulation of the ferric uptake regulatory gene of Campylobacter jejuni TGH9011

Chan, Vivien; Louie, Helena; Bingham, Hermine L.

doi:10.1016/0378-1119(95)00477-n

Cited by 25 publications

(38 citation statements)

References 35 publications

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“…There are two copies of sequences resembling Fur binding boxes (9,13,58) in the intergenic region, but these map closer to cfrA than to tonB. The regulation of these two genes and the nature of adjacent coding sequences are currently under investigation.…”

Section: Discussionmentioning

confidence: 99%

A genetic locus involved in iron utilization unique to some Campylobacter strains

et al. 1997

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Two genes involved in iron utilization in Campylobacter coli VC167 T1 have been characterized. The cfrA gene encodes a protein with a predicted M r of 77,653 which, after processing of the leader sequence, has a predicted M r of 75,635. This protein has significant sequence identity to siderophore receptors of several bacteria, and site-specific mutants defective in cfrA do not synthesize one of two major iron-repressible outer membrane proteins. An adjacent gene encodes a TonB-like protein; a mutant in this gene lost the ability to utilize hemin, ferrichrome, and enterochelin as iron sources. The cfrA and tonB genes of VC167 T1 hybridized to all strains of C. coli and most strains of C. jejuni examined but did not hybridize to several other strains of C. jejuni, suggesting that the thermophilic campylobacters can be separated into two categories based on the presence of these two iron utilization genes.

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Section: Discussionmentioning

confidence: 99%

A genetic locus involved in iron utilization unique to some Campylobacter strains

et al. 1997

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“…Thus, an iron-responsive regulatory circuit similar to the Fur system probably regulates a subset of virulence-associated genes in C. jejuni. Wooldridge et al (1994) and now others (Chan et al, 1995) have cloned the fur gene from C . jejuni.…”

Section: Regulation By Furmentioning

confidence: 99%

Pathogenesis of Enteric Infection by Campylobacter

1997

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“…The CDM medium used for the determination of JlpA expression has been described in detail by Tenover et al (1985). Low-iron and high-iron CDM broth media were prepared according to the method of Chan et al (1995). E. coli strains were grown in Luria±Bertani (LB) medium at 378C.…”

Section: Bacterial Strains Plasmids and Culture Conditionsmentioning

confidence: 99%

JlpA, a novel surface-exposed lipoprotein specific to Campylobacter jejuni, mediates adherence to host epithelial cells

Jin

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Lynett³

et al. 2001

Mol Microbiol

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Cloning and transcription regulation of the ferric uptake regulatory gene of Campylobacter jejuni TGH9011

Cited by 25 publications

References 35 publications

A genetic locus involved in iron utilization unique to some Campylobacter strains

A genetic locus involved in iron utilization unique to some Campylobacter strains

Pathogenesis of Enteric Infection by Campylobacter

JlpA, a novel surface-exposed lipoprotein specific to Campylobacter jejuni, mediates adherence to host epithelial cells

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