Cloning and characterization of tyrosine hydroxylase (TH) from the pacific white leg shrimp Litopenaeus vannamei , and its expression following pathogen challenge and hypothermal stress

Mapanao, Ratchaneegorn; Cheng, Winton

doi:10.1016/j.fsi.2016.08.016

Cited by 23 publications

(3 citation statements)

References 41 publications

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“…The gene coding TH has been identified from various species of nonvertebrates, including shrimp (454), fresh water crab [D. pagei (615)], parasitic helminthes [Schistosoma mansoni (258), Schistosoma japonicum (294)], and insects [Drosophila (760), moth (300), cricket (862)]. In several species of insects, as in mammals, different isoforms of TH produced by alternative splicing have been identified [in the cricket (862) and in D. melanogaster and the armyworm M. separata (62,534)].…”

Section: Evolution Of Tyrosine Hydroxylase a Key Enzyme Of Dopamine Synthesismentioning

confidence: 99%

Origin and Evolution of the Neuroendocrine Control of Reproduction in Vertebrates, With Special Focus on Genome and Gene Duplications

Dufour

Quérat

Tostivint

et al. 2020

Physiological Reviews

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In humans, as in the other mammals, the neuroendocrine control of reproduction is ensured by the brain-pituitary gonadotropic axis. Multiple internal and environmental cues are integrated via brain neuronal networks, ultimately leading to the modulation of the activity of gonadotropin-releasing hormone (GnRH) neurons. The decapeptide GnRH is released into the hypothalamic-hypophysial portal blood system and stimulates the production of pituitary glycoprotein hormones, the two gonadotropins luteinizing hormone and follicle-stimulating hormone. A novel actor, the neuropeptide kisspeptin, acting upstream of GnRH, has attracted increasing attention in recent years. Other neuropeptides, such as gonadotropin-inhibiting hormone/RF-amide related peptide, and other members of the RF-amide peptide superfamily, as well as various nonpeptidic neuromediators such as dopamine and serotonin also provide a large panel of stimulatory or inhibitory regulators. This paper addresses the origin and evolution of the vertebrate gonadotropic axis. Brain-pituitary neuroendocrine axes are typical of vertebrates, the pituitary gland, mediator and amplifier of brain control on peripheral organs, being a vertebrate innovation. The paper reviews, from molecular and functional perspectives, the evolution across vertebrate radiation of some key actors of the vertebrate neuroendocrine control of reproduction and traces back their origin along the vertebrate lineage and in other metazoa before the emergence of vertebrates. A focus is given on how gene duplications, resulting from either local events or from whole genome duplication events, and followed by paralogous gene loss or conservation, might have shaped the evolutionary scenarios of current families of key actors of the gonadotropic axis.

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Section: Evolution Of Tyrosine Hydroxylase a Key Enzyme Of Dopamine Synthesismentioning

confidence: 99%

Origin and Evolution of the Neuroendocrine Control of Reproduction in Vertebrates, With Special Focus on Genome and Gene Duplications

Dufour

Quérat

Tostivint

et al. 2020

Physiological Reviews

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“…Sepiapterin reductase plays a key role in the biosynthesis of BH4, the essential cofactor for multiple enzymes, including Pah, Th, Tph, and Nos. Among these enzymes, Th and Nos have been identified in L. vannamei ( Yao et al, 2010 ; Mapanao and Cheng, 2016 ). In vivo knockdown of LvSpr in L. vannamei was performed via injection of dsRNA, followed by WSSV challenge, to investigate the potential functional role of LvSpr in the regulation BH4-dependent enzymes.…”

Section: Resultsmentioning

confidence: 99%

“…Th and Nos are closely associated with invertebrate innate immunity. The genes encoding L. vannamei Th and Nos have been cloned ( Yao et al, 2010 ; Mapanao and Cheng, 2016 ). In the present study, the two enzymes’ activity was analyzed in shrimp treated with LvSpr dsRNA or LvSpr dsRNA + WSSV infection to investigate if these two genes were involved in Spr-mediated immune response.…”

Section: Discussionmentioning

confidence: 99%

WSV056 Inhibits Shrimp Nitric Oxide Synthase Activity by Downregulating Litopenaeus vannamei Sepiapterin Reductase to Promote White Spot Syndrome Virus Replication

et al. 2021

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Sepiapterin reductase (Spr) plays an essential role in the biosynthesis of tetrahydrobiopterin (BH4), a key cofactor of multiple enzymes involved in various physiological and immune processes. Suppression of Spr could result in BH4 deficiency-caused diseases in human and murine models. However, information on the biological function of Spr in invertebrates is limited. In this study, two Sprs (CG12116 and Sptr) from Drosophila melanogaster were found to be downregulated in transgenic flies overexpressing white spot syndrome virus (WSSV) immediate-early protein WSV056. CG12116 and Sptr exerted an inhibitory effect on the replication of the Drosophila C virus. A Litopenaeus vannamei Spr (LvSpr) exhibiting similarity of 64.1–67.5% and 57.3–62.2% to that of invertebrate and vertebrate Sprs, respectively, were cloned. L. vannamei challenged with WSSV revealed a significant decrease in LvSpr transcription and Spr activity in hemocytes. In addition, the BH4 co-factored nitric oxide synthase (Nos) activity in shrimp hemocytes was reduced in WSSV-infected and LvSpr knockdown shrimp, suggesting WSSV probably inhibits the LvNos activity through LvSpr downregulation to limit the production of nitric oxide (NO). Knockdown of LvSpr and LvNos caused the reduction in NO level in hemocytes and the increase of viral copy numbers in WSSV-infected shrimp. Supplementation of NO donor DETA/NO or double gene knockdown of WSV056 + LvSpr and WSV056 + LvNos recovered the NO production, whereas the WSSV copy numbers were decreased. Altogether, the findings demonstrated that LvSpr and LvNos could potentially inhibit WSSV. In turn, the virus has evolved to attenuate NO production via LvSpr suppression by WSV056, allowing evasion of host antiviral response to ensure efficient replication.

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Cyclin-dependent Kinase 1 (CDK1) in Pacific white shrimp (Litopenaeus vannamei): Molecular characterization and its role in response to cold stress

Chen

Lü

Chen

et al. 2023

Aquaculture Reports

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Cloning and characterization of tyrosine hydroxylase (TH) from the pacific white leg shrimp Litopenaeus vannamei , and its expression following pathogen challenge and hypothermal stress

Cited by 23 publications

References 41 publications

Origin and Evolution of the Neuroendocrine Control of Reproduction in Vertebrates, With Special Focus on Genome and Gene Duplications

Origin and Evolution of the Neuroendocrine Control of Reproduction in Vertebrates, With Special Focus on Genome and Gene Duplications

WSV056 Inhibits Shrimp Nitric Oxide Synthase Activity by Downregulating Litopenaeus vannamei Sepiapterin Reductase to Promote White Spot Syndrome Virus Replication

Cyclin-dependent Kinase 1 (CDK1) in Pacific white shrimp (Litopenaeus vannamei): Molecular characterization and its role in response to cold stress

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