Cloneable Selenium Nanoparticles As Multi-modal Bio-imaging Contrast Agents
Kanda Borgognoni,
Bradley Guilliams,
Rachel Cohen
et al.
Abstract:A cloneable NanoParticle (cNP) is an inorganic nanoparticle that is synthesized by a protein. The protein determines the elemental composition, size, morphology, and other properties of the nanoparticle. Here, we describe the use of a cloneable Selenium NanoParticle (cSeNP) as a cloneable imaging contrast agent in electron microscopy, fluorescence microscopy, and X-ray computed tomography. Combined, these three imaging modalities produce images of biological length scales spanning meters to angstroms but are d… Show more
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