Abstract:Clomipramine Delirium: 2 case reportsTwo women, aged 61 and 67 years, with major depressive disorder developed delirium after IV clomipramine was added to their regimen of oral clomipramine, and the plasma concentration of the agent became acutely elevated.Both women started oral clomipramine with the dosage increased over 3 and 6 weeks, respectively, to 150 mg/day [duration of therapy not stated]. Their plasma clomipramine concentrations were 150 and 148 ng/ml and their plasma desmethylclomipramine concentrat… Show more
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