Clock protein LHY targets
SNAT1
and negatively regulates the biosynthesis of melatonin in
Hypericum perforatum
Wen Zhou,
Ru-Yi Xiao,
Yi-Xiao Yang
et al.
Abstract:Hypericum perforatum
, also known as “natural fluoxetine,” is a commonly used herbal remedy for treating depression. It is unclear whether melatonin in plants regulated by the endogenous circadian clock system is like in vertebrates. In this work, we found that the melatonin signal and melatonin biosynthesis gene, serotonin
N
-acetyltransferase
HpSNAT1
, oscillates in a 24-hour cycle in
H. perforatum
. First, we constructed a y… Show more
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