Clinopodium chinense Kuntze ameliorates dextran sulfate sodium-induced ulcerative colitis in mice by reducing systematic inflammation and regulating metabolism

Plant-based milk alleviates antibiotics-induced intestinal barrier damage associated with modulation of gut microbiome and metabolome

“…The differential metabolites altered by plant-based milk compared to CS mice were essentially lipid, amino acid, and vitamin-like compounds, which was consistent with previous studies [15] . Notably, amino acids are important active molecules in living organisms, the Alanine, aspartate and glutamate metabolism are core metabolic pathway, has important implications in various amino acid metabolisms [79] . Amino acids, which were researched that are vital nutrients for improving intestinal mucosal integrity and maintaining intestinal barrier function [80,81] .…”

Triterpenoids from Meehania fargesii with Cytotoxic Activity1

“…AGS cells were cultured in RPMI 1640 medium containing 10 % fetal bovine serum, and maintained in a constant temperature incubator set at 37 °C with 5 % CO 2 . After attachment, the cells were pretreated with the test compounds in different concentrations for 24 h. Then, 10 μL CCK‐8 was added to the cells and incubated for 4 h. Absorbance was measured by a microplate reader at 450 nm [26] . Oxaliplatin were used as positive controls in these cytotoxic assays.…”

“…After attachment, the cells were pretreated with the test compounds in different concentrations for 24 h. Then, 10 μL CCK-8 was added to the cells and incubated for 4 h. Absorbance was measured by a microplate reader at 450 nm. [26] Oxaliplatin were used as positive controls in these cytotoxic assays. Growth inhibition rate (%) = (Ac-As)/(Ac-Ab)×100 %.…”