Clinicopathological Study of Liver Abscess in Eastern Indian Population

Abstract

BACKGROUND A descriptive study of Liver abscess is defined as collection of purulent material in liver parenchyma. It could be amoebic, pyogenic, infected hydatid, traumatic or ascaridal. It is a burning problem in tropical nations with often lethal consequences and diagnostic/therapeutic challenges. This study aims to find out the demographic distribution, different modes of presentations, risk factors association, alteration of various laboratory and radiological investigations in diagnosis of liver abscess and responses to standard institutional management strategies. MATERIALS AND METHODS Medical records were taken by preformed case, Proforma. Descriptive statistics were used and analysed by SPSS software. RESULTS 3/4th of cases belonged to 4th to 6th decade. Males were more commonly affected than females. Alcoholism was the most consistent risk factor followed by diabetes mellitus. Most common presenting symptom and sign were abdominal pain and abdominal tenderness in right hypochondriac region respectively. Most common aetiology of liver abscess was amoebic followed by mixed amoebic and pyogenic infections. The most common organisms obtained from pus C/S from liver abscess were Enterococcus spp. and Escherichia coli. Abnormal chest x-ray findings were recorded in > 50% of cases. USG showed majority of cases had large, solitary liver abscess in right lobe of liver. Most common complication observed was intraabdominal rupture of liver abscess, for which open surgical drainage was performed. CONCLUSION Recurrence was observed more following conservative management than other modalities.