“…Concerning autoantibodies, it is reported that the titers of ASMA or ANA are lower in Asian patients with AIH or PBC–AIH overlap syndrome . Moreover, we have previously found that AIH in the acute phase shows lower ANA titers than AIH in the chronic hepatitis phase . Therefore, we modified these factors when devising our criteria for PBC patients with AIH features.…”
Patients with PBC with AIH features benefit from corticosteroid therapy. Features of PBC such as high ALP level, negativity for ASMA and positivity for gp210 appear to predict a poor response to corticosteroids.
“…Concerning autoantibodies, it is reported that the titers of ASMA or ANA are lower in Asian patients with AIH or PBC–AIH overlap syndrome . Moreover, we have previously found that AIH in the acute phase shows lower ANA titers than AIH in the chronic hepatitis phase . Therefore, we modified these factors when devising our criteria for PBC patients with AIH features.…”
Patients with PBC with AIH features benefit from corticosteroid therapy. Features of PBC such as high ALP level, negativity for ASMA and positivity for gp210 appear to predict a poor response to corticosteroids.
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