Clinicopathological features of incidental parotid lesions

Al‐Balas, Hassan; Metwalli, Zeyad; Eberson, Sarah; Sada, David M.

doi:10.1186/s13005-021-00262-6

Cited by 9 publications

(11 citation statements)

References 21 publications

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“…In addition, most of the parotid lesions (81.6%) were located in the superficial lobe, which is consistent with the results of previous studies that described the imaging characteristics of parotid lesions [ 18 , 19 , 20 ]. However, only four patients had bilateral parotid lesions, which is inconsistent with previous studies, which reported up to 25% [ 16 , 18 , 19 , 20 ]. The reason for this discrepancy is unclear, but it is probably related to the differences in the number of enrolled study patients and the histopathology of the lesions.…”

Section: Discussioncontrasting

confidence: 99%

“…In the current study, the average size of the lesions was 1.3 cm, similar to the results of a previous study, suggesting that the small size of parotid lesions is a possible cause of asymptomatic conditions [16]. In addition, most of the parotid lesions (81.6%) were located in the superficial lobe, which is consistent with the results of previous studies that described the imaging characteristics of parotid lesions [18][19][20].…”

Section: Discussionsupporting

confidence: 92%

“…However, the prevalence of incidental parotid lesions based on CT and MRI is still unknown. To the best of our knowledge, only a single retrospective study reviewed incidental parotid lesions on CT, MRI, and PET imaging [ 16 ]. Therefore, we retrospectively assessed the prevalence and clinical implications of incidental parotid lesions as blind spots detected only on brain MRI.…”

Section: Discussionmentioning

confidence: 99%

“…A few imaging studies have reported the presence of unexpected asymptomatic parotid lesions; however, these studies mainly focused on parotid lesions detected via 18-F fluorodeoxyglucose (FDG) positron emission tomography (PET) or PET–computed tomography (CT) [ 11 , 12 , 13 , 14 , 15 ]. In contrast, the clinical significance of incidental parotid lesions detected via other more commonly utilized imaging modalities remains unclear [ 16 ]. Furthermore, the frequency of the incidental findings in previous studies has varied according to the imaging modality used and the area of interest investigated [ 11 , 12 , 13 , 14 , 15 , 16 ].…”

Section: Introductionmentioning

confidence: 99%

“…In contrast, the clinical significance of incidental parotid lesions detected via other more commonly utilized imaging modalities remains unclear [ 16 ]. Furthermore, the frequency of the incidental findings in previous studies has varied according to the imaging modality used and the area of interest investigated [ 11 , 12 , 13 , 14 , 15 , 16 ]. Therefore, the purpose of our retrospective study was to assess the prevalence and clinical implications of incidental parotid lesions as potential blind spots detected during brain MRI examination.…”

Section: Introductionmentioning

confidence: 99%

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Prevalence and Clinical Implications of Incidentally Detected Parotid Lesions as Blind Spot on Brain MRI: A Single-Center Experience

et al. 2021

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Background and objective: This study was conducted to assess the prevalence and clinical implications of parotid lesions detected incidentally during brain magnetic resonance imaging (MRI) examination. Materials and Methods: Between February 2016 and February 2021, we identified 86 lesions in the brain MRI reports of 84 patients that contained the words “parotid gland” or “PG”. Of these, we finally included 49 lesions involving 45 patients following histopathological confirmation. Results: Based on the laboratory, radiological or histopathological findings, the prevalence of incidental parotid lesions was low (1.2%). Among the 45 study patients, 41 (91.1%) had unilateral lesions, and the majority of the lesions were located in the superficial lobe (40/49, 81.6%). The mean size of the parotid lesions was 1.3 cm ± 0.4 cm (range, 0.5 cm–2.8 cm). Of these, 46 parotid lesions (93.9%) were benign, whereas the remaining three lesions were malignant (6.1%). Conclusions: Despite the low prevalence and incidence of malignancy associated with incidental parotid lesions detected on brain MRI, the clinical implications are potentially significant. Therefore, clinical awareness and appropriate imaging work-up of these lesions are important for accurate diagnosis and timely management.

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Section: Discussioncontrasting

confidence: 99%

Section: Discussionsupporting

confidence: 92%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Prevalence and Clinical Implications of Incidentally Detected Parotid Lesions as Blind Spot on Brain MRI: A Single-Center Experience

et al. 2021

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Risk of Carcinoma in Pleomorphic Adenomas of the Parotid

Levyn,

Subramanian,

Eagan

et al. 2023

JAMA Otolaryngol Head Neck Surg

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ImportanceSurgery is the mainstay of treatment for pleomorphic adenomas (PAs) of the parotid to prevent further growth and potential future malignant transformation. While historical case series have reported transformation rates as high as 10%, there is a lack of contemporary methodologically sound data.ObjectiveTo examine the rate of carcinoma ex pleomorphic adenoma (CXPA) detection in untreated PAs and investigate factors associated with malignant neoplasm.Design, Setting, and ParticipantsThis cohort study reviewed all cases of primary PAs managed at a quaternary referral center between December 1990 and January 2015. Patients whose clinical presentation was compatible with a primary benign PA and whose history indicated tumor duration of over 1 year were included. Data were analyzed from January to April 2023.ExposureUntreated PA.Main Outcomes and MeasuresRate of CXPA detection among untreated PAs and association of tumor duration with rates of CXPA detection. Pathology slides of patients who underwent surgery were reviewed by a single expert pathologist for the presence of CXPA. Univariable logistic regression was performed to evaluate possible factors associated with CXPA.ResultsA total of 260 patients (median age, 47 years [IQR, 38-60 years]; 174 [66.9%] female) had a median tumor duration of 3.2 years (range, 1-30 years; mean [SD], 5.7 [5.5] years). Patients were divided into 4 groups by tumor duration: 1 to 4 years (158 [60.7%]), 5 to 9 years (47 [18.1%]), 10 to 14 years (27 [10.4%]), and 15 to 30 years (28 [10.8%]). In 156 of 170 patients who underwent preoperative fine-needle aspiration (91.8%), a benign tumor was diagnosed; 5 of these patients (3.2%; 95% CI, 1.4%-7.3%) were later diagnosed with CXPA on pathology after eventual excision, and the rate of high grade CXPA was 1.3%. None of the patients had permanent facial nerve paralysis. Tumor size at presentation (odds ratio [OR], 1.66; 95% CI, 1.22-2.24) and incremental (per year) increase in age (OR, 1.04; 95% CI, 1.01-1.08) were found to be associated with CXPA, whereas tumor duration was not (OR, 1.00; 95% CI, 1.00-1.01).Conclusions and RelevanceIn this study, the rate of malignant neoplasm detection among initially untreated PA was 3.2%. The results suggest that tumor size and older age are associated with the development of CXPA, while tumor duration is not. Observation of PA for longer periods was not associated with serious permanent complications.

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Minimally invasive retroauricular approach parotidectomy: A pictorial essay

Sethi

Fundakowski

2023

Head & Neck

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The surgical approach to a parotid neoplasm has traditionally been taught through a modified-Blair incision. This approach results in a visible scar in the preauricular, retromandibular, and upper neck skin. Various modifications have been undertaken which aim to improve cosmesis either by decreasing overall incision length and/or relocation of the incision to the hairline via what is commonly described as a "facelift approach". We describe a novel minimally invasive parotidectomy approach which utilizes a single retroauricular incision. This approach eliminates both the preauricular scar as well as the extended incision in the hairline and additional skin flap elevation which accompanies it. Sixteen patients underwent parotidectomy using this minimally invasive incision and the excellent clinical outcomes are reviewed. The minimally invasive retroauricular approach to parotidectomy provides excellent exposure with no visible incision/scar in appropriately selected patients.

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Clinicopathological features of incidental parotid lesions

Cited by 9 publications

References 21 publications

Prevalence and Clinical Implications of Incidentally Detected Parotid Lesions as Blind Spot on Brain MRI: A Single-Center Experience

Prevalence and Clinical Implications of Incidentally Detected Parotid Lesions as Blind Spot on Brain MRI: A Single-Center Experience

Risk of Carcinoma in Pleomorphic Adenomas of the Parotid

Minimally invasive retroauricular approach parotidectomy: A pictorial essay

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