Clinicopathological features of esophageal cancer simultaneously associated with gastric cancer

Synchronous primary esophageal squamous cell carcinoma and gastric adenocarcinoma: analysis of 41 cases treated in a single institution

“…The association of esophageal cancer with head and neck cancer has been demonstrated 3 4 5 6 7 ; however, a high incidence of synchronous gastric cancer has also been reported, especially in East Asia 8 9 10 . In the present study, the incidence of synchronous primary esophageal squamous cell carcinoma and gastric adenocarcinoma was low compared to that reported previously, despite the large number of patients diagnosed with esophageal cancer in the Chaoshan region of Southern China.…”

Carcinoma epidermóide de esôfago e adenocarcinoma gástrico sincrônicos

“…The squamous cell carcinoma of the esophagus has been described in association with gastric adenocarcinoma primarily in Japan in 1980; data from the Japanese Committee for Diseases of the Esophagus showed that of the 11,732 cases of esophageal tumors resected in Japan 186 (1.6 %) were tumor-associated with gastric tumors 7 . Hamabe et al 8 , in a retrospective study of 288 patients with primary tumors of the esophagus resected, obtained 17 (5.9%) with concomitant second primary tumor. Of these, 11 (3.8%) were adenocarcinoma, being all male.…”

Simultaneous presentation of oesophageal and renal cancer

“…Oesophageal squamous cell carcinoma has been reported to be frequently associated with multiple primary neoplasms (MPN) such as cancers of the head and neck or stomach [1][2][3][4][5][6]. MPN that occur concurrently or within 6 months of identification of the primary lesion are defined as synchronous tumours based on the criteria proposed by Warren and Gates: malignancy should be confirmed by histological examination, the tumours must be separated by normal mucosa and the possibility that the second neoplasm represents a metastasis must be excluded [3,4,7,8].…”

“…Reports indicate that the operative mortality and pulmonary morbidity rate after oesophagectomy in patients with synchronous tumours are similar to those in patients with solitary oesophageal cancer [5,8]. In order to decrease the surgical risk, an adequate operative approach must be chosen, taking into account the stage of both neoplasms, the patient's general condition, especially preoperative pulmonary and renal function, and also the stress caused by aggressive surgery [1,2]. Thus, for each patient, the risks and benefits of simultaneous surgery should be weighed against those of a second operation [6].…”

“…Several studies have demonstrated a high incidence of oesophageal cancer occurring in association with cancers of the head and neck or stomach [1][2][3][4][5][6]. On the contrary, the simultaneous presentation of oesophageal and renal cell carcinoma is rarely encountered clinically.…”