Clinicopathological features and outcomes following for primary branchiogenic carcinoma: A case report

Nguyen, Van Chu; Phung, Thi Huyen; Thi, Phuong Hoa Nguyen

doi:10.1016/j.ehpc.2020.200362

Cited by 1 publication

(2 citation statements)

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“…In some cases, the tumor seems to be aggressive with a significant incidence of local recurrence, multiple nodal metastases, often bilateral, and poor outcome [ 8 , 30 ]. The extent of the disease is correlated to the prognosis [ 31 ]. Relevant literature suggests that the therapeutic approach must be aggressive including wide local excision, neck dissection, and adjuvant radiotherapy and/or chemotherapy, when an invasion of surrounding tissue or cervical lymph nodes is present, in order to prevent a recurrence [ 31 ].…”

Section: Discussionmentioning

confidence: 99%

“…The extent of the disease is correlated to the prognosis [ 31 ]. Relevant literature suggests that the therapeutic approach must be aggressive including wide local excision, neck dissection, and adjuvant radiotherapy and/or chemotherapy, when an invasion of surrounding tissue or cervical lymph nodes is present, in order to prevent a recurrence [ 31 ].…”

Section: Discussionmentioning

confidence: 99%

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Clinical Controversy Surrounding the Differential Diagnosis of Branchiogenic Carcinoma

Karatzanis

Mylopotamitaki

Lagoudaki

et al. 2022

Case Reports in Otolaryngology

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Clinical evaluation, di erential diagnosis, and management of a neck mass constitute commonly encountered problems for the head and neck surgeon. An asymptomatic neck mass in adults may be the only clinical sign of head and neck cancer. A 50-year-old female patient presented with a painless, slowly enlarging, left lateral neck lump. Ultrasonography described a possible lymph node with cystic degeneration, and ne needle aspiration biopsy only detected atypical cells of squamous epithelium. An open biopsy under general anesthesia was performed. Histopathological ndings suggested the diagnosis of lymph node in ltration by squamous cell carcinoma of an unknown primary site, but di erential diagnosis also included branchiogenic carcinoma arising in a branchial cleft cyst. A diagnostic algorithm for metastatic squamous cell carcinoma of an unknown primary site was followed, including positron emission tomography with computed tomography.e patient underwent panendoscopy and bilateral tonsillectomy, and an ipsilateral p16 positive tonsillar squamous cell carcinoma was detected. Further appropriate management followed. e existence of true branchiogenic carcinoma is controversial. When such a diagnosis is contemplated, every e ort should be made to detect a possible primary site. Branchiogenic carcinoma, if exists at all, remains a diagnosis of exclusion.

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