Clinicopathological Determinants of Vaginal and Premalignant-Malignant Cervico-Vaginal Polyps of the Lower Female Genital Tract

Fauth, Clarissa T.; Franko, Angela; Duan, Quili; Wood, Stephen L.; Duggan, Máire A.

doi:10.1097/lgt.0b013e31820b7e0f

Cited by 7 publications

(3 citation statements)

References 18 publications

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“…This incidence was higher in the postmenopausal group than in the perimenopausal group. Other studies that performed endometrial sampling in addition to polypectomy reported endometrial carcinoma rates from 0.1% to 0.4% in postmenopausal women with cervical polyps [25,26]. Few studies have observed that cervical polyps are often associated with endometrial hyperplasia, which suggests that high levels of estrogen may have a significant etiologic role, and they constitute 4-10% of all cervical lesions [2,3].…”

Section: Discussionmentioning

confidence: 99%

Cervical polyp: evaluating the need of routine surgical intervention and its correlation with cervical smear cytology and endometrial pathology: a retrospective study

et al. 2020

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Objective To determine the frequency of premalignant and malignant lesions in cervical polyps in order to examine whether cervical polyps need to be removed routinely and also to appraise its association with cervical smear cytology and endometrial pathologies. Methods We retrospectively reexamined the hospital records of 299 cases over a period of 5 years. All patients were segregated into perimenopausal and postmenopausal groups according to their menopausal status. The groups were compared in terms of histological results of cervical polyp biopsy, endometrial pathologies, and cervical smear cytology. Pearson's χ 2 test and Fisher's exact test were used for statistical analysis, and a P-value of <0.05 was accepted as statistically significant. Results In the histopathological reports of cervical polyps, premalignant lesions were found in 2% of cases, and only 0.3% of malignant lesion was observed in menopausal women. Subsequently, no malignancy was noted in cervical smear cytology for both groups. Premalignant and malignant lesions in endometrial histopathology findings were 1.33% and 0.66%, respectively. There was a statistically significant association between the menopausal status of the patient and cervical smear cytology and endometrial pathology, but the histological findings were not statistically significant in relation to the symptomatic status of the patients. Conclusion As per the results, we strongly suggest the removal of all cervical polyps with subsequent histological review. The evaluation of cervical smear cytology prior to polypectomy can provide information about its malignancy potential. We believe that along with cervical polypectomy, endometrial sampling should be recommended, especially for postmenopausal women.

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Section: Discussionmentioning

confidence: 99%

Cervical polyp: evaluating the need of routine surgical intervention and its correlation with cervical smear cytology and endometrial pathology: a retrospective study

et al. 2020

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“…Authors concluded that malignant UCP were more frequent in patients over 60 (8). In a study from Mayo Clinic, 4328 polyps were evaluated in 3656 patients.…”

Section: Discussionmentioning

confidence: 99%

Serviks poliplerinin klinikopatolojik değerlendirmesi

Şentürk

Budak

Durukan

et al. 2015

ZKTB

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Objective: Management of uterine cervical polyps is a common debate in clinical practice. Ethical concerns complicate decision making as well as designing randomized or prospective studies. Thus, clinical evidence can be gathered from retrospective studies. Possibility of malignant transformation is also a concern in assessment and management of pre-and post-menopausal patients. In this study we aimed to identify if a difference exist in between these groups, and discuss our results with the previously reported. Material and Method:We evaluated results of 245 patients retrospectively. Totally 270 polyps were detected. Pathological results of polyps were compared according to menopausal status and symptoms. Fisher's Exact Test and Fisher-Freeman-Halton Test were used in statistical analysis. Statistical significance is considered where p<0.05 and p<0.01. Results:There was no invasive disease. Cervical intraepithelial neoplasia type 1 was seen in one postmenopausal patient. Polyps were asymptomatic in 39.6% (n=97) of the cases and coincide with abnormal uterine bleeding (AUB) in 53.9% (n=132), and missed abortus in 6.5% (n=16). Patients with polyps significantly tend to have complaint of abnormal uterine bleeding compared to other symptoms. Conclusion:Routine cervical polypectomy is not necessary. Cytology and utilization of colposcopy should be considered prior to polypectomy, as well as assessment of clinical and menopausal status.

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“…They are usually diagnosed incidentally on vaginal examination and appear as soft, glistening, friable, cherry-red to reddish-purple lesions that bleed upon contact. Most cervical polyps are <2 cm, and a larger size is associated with a higher incidence of malignancy [ 1 ]. Although the exact etiology of cervical polyps is unknown, they are thought to arise secondary to reactive changes from high circulating hormone levels in cases of chronic inflammation and from the congestion of blood vessels in the cervix secondary to increased levels of estrogen or else are idiopathic in nature.…”

Section: Introductionmentioning

confidence: 99%

Role of Ultrasound in Managing Cervical Polyps During Pregnancy

Kondagari¹,

Josephs

2021

Cureus

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No definitive management guidelines exist for cervical polyps during pregnancy. Ultrasound can aid in creating a treatment plan by assessing the type of polyp and source of symptomatology. Three pregnant patients in the first, second, and third trimesters of pregnancy presented with polyps. On examination, the polyps ranged from 2 to 6 cm in size. In all cases, the origin of the cervical polyps was first identified on ultrasound. Polypectomies were performed with no complications. All patients subsequently had uncomplicated normal spontaneous vaginal deliveries at term. Ultrasounds can help localize the source of symptomatology to polyps versus placental pathology. Additionally, ultrasound can determine the origin and type of polyp for creating an individualized, safe treatment plan during pregnancy.

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Clinicopathological Determinants of Vaginal and Premalignant-Malignant Cervico-Vaginal Polyps of the Lower Female Genital Tract

Abstract: Vaginal polyps and premalignant-malignant cervico-vaginal polyps are rare. Vaginal polyps are larger and multiple and cervico-vaginal polyps in younger and older women are at greater risk of premalignant-malignant changes.

Cited by 7 publications

References 18 publications

Cervical polyp: evaluating the need of routine surgical intervention and its correlation with cervical smear cytology and endometrial pathology: a retrospective study

Cervical polyp: evaluating the need of routine surgical intervention and its correlation with cervical smear cytology and endometrial pathology: a retrospective study

Serviks poliplerinin klinikopatolojik değerlendirmesi

Role of Ultrasound in Managing Cervical Polyps During Pregnancy

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