Clinicopathological characteristics, diagnosis and treatment of melanoma in Serbia: The Melanoma Focus Study

Kandolf-Sekulović, Lidija; Babović, Nada; Balic, M.; Nikolin, Borislava; Nikolić, Dejan; Janjić, Zlata; Jokić, N; Mijušković, Željko; Rajović, Milica; Novakovic, Marijan; Vrbić, Svetislav; Pejčić, Ivica; Kovačević, Predrag; Mihajlović, Dragan; Roganović, Tatjana; Vicko, Ferenc; Nikolić, Jelena; Marinković, Mirjana Marković; Bizetic, Zorana

doi:10.2298/vsp131014052k

Cited by 3 publications

(3 citation statements)

References 8 publications

(8 reference statements)

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“…Our results show no statistical difference in the incidence of different types of melanomas between men and women. SM was the most common type of melanoma (68.7%), followed by NM (15.4%), LM (10.4%) and AM (1.0%), coinciding with the results published for the US and EU [19]. Comparisons of anatomic localizations at UV-exposed regions, as expected, showed LM presence most commonly on the head and neck regions (61.9%), while AM was present on the lower extremities only [9].…”

Section: Discussionsupporting

confidence: 86%

Clinicopathologic characteristics of cutaneous melanoma - A single-center retrospective study

et al. 2022

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Introduction/Objective Epidemiology of melanoma including the number of new cases and mortality have been established in most developed countries, but data on pathohistological features are mostly missing. The objective of the study was to investigate epidemiological, clinical and pathohistological features of melanoma patients and compare the results with trends in other countries. Methods Our sample comprised patients surgically treated for skin melanoma at the Hospital for Burns, Plastic and Reconstructive Surgery during 2015-2017. Pathohistological, clinical and demographic features of melanoma were studied. Results The retrospective study comprised 201 patients (109 men and 92 women) aged 25-87 years. Melanoma was more common in men than in women (54.2% vs. 45.8%). Melanoma in male population most commonly presented on the trunk, while in female on the trunk and lower extremities was almost the same. Superficial spreading melanoma was the most common type of melanoma (68.7%), without correlation with the gender. No correlation was observed in relation to the stage of the disease and patient?s sex (p = 0.294). A statistical difference was observed in relation to the type of melanoma and the Breslow classification (p < 0.001). Breslow?s thickness did not correlate with age nor with sex. In relation to tumor invasiveness, 12.4% of the lesions were classified as in situ lesions, while 87.6% lesions were invasive. The majority of patients were identified as stage pT1a. Conclusion This study can help to identify patients at high risk for melanoma and contribute to optimize screening efforts in a defined target population.

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Section: Discussionsupporting

confidence: 86%

Clinicopathologic characteristics of cutaneous melanoma - A single-center retrospective study

et al. 2022

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“…The age‐standardized incidence rate of melanoma is 5.4/100 000 (males) and 4.9/100 000 (females), and mortality rates are 2.5/100 000 (males) and 1.2/100 000 (females), with rising trends in both of them . Relatively low incidence rates in central Serbia are accompanied by a large percentage of thick tumours (median Breslow thickness of melanoma was 3 mm; primary tumours with the thickness of more than 4 mm were found in 31.95–50% of patients) and a significant proportion of younger patients with thick tumours . This indicates the fundamental need for more effective primary and secondary prevention activities.…”

Section: Introductionmentioning

confidence: 99%

Ultraviolet radiation exposure among Belgrade high school students: analysis of knowledge, attitudes and behaviour

Škiljević

Sreckovic

2019

Acad Dermatol Venereol

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Background The incidence of melanoma has been increasing worldwide. Extended UV exposure during childhood or adolescence significantly increases the probability of skin cancer in adulthood. Objective The objective of this study was to analyse knowledge, attitudes and behaviour regarding exposure to natural and artificial UV radiation among Belgrade high school students. Methods The study was conducted using a questionnaire among 549 students of 3rd and 4th grade (17 and 18 years of age) in four Belgrade high schools. The questionnaire had 32 questions: questions about gender, date and month of birth and parents’ education, nine questions regarding sunbed use, nine questions regarding behaviour in the sun during summer months, four questions regarding personal and family history and skin phototype and seven questions regarding attitude and general knowledge about effects of UV radiation. Assessment of frequency rate and relative numbers was used as methods of descriptive statistics. Results As many as 39% of participants had used a sunbed at least once, 38% plan on using it in the future. One quarter spends more than 3 hours in the sun on the beach during summer without any protection, and only one‐third of participants had not experienced sunburn during last summer. Only one‐half of students know what melanoma is, while 37% stated that they do not know. Conclusion General awareness of risk factors regarding sun exposure as well as general knowledge about melanoma is not on a high level among Belgrade high school students. Therefore, besides legislative measures, it is extremely important to conduct adequate education programmes in high schools.

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“…The liver is a frequent site of metastases from a variety of cancers including gastric, breast, melanoma, and pancreatic with colorectal cancer being the most common source. [1][2][3][4][5] Although surgical resection of metastatic lesions has proven effective and improves overall survival, many patients develop extensive or unresectable diseases not amenable to surgery. Regardless of the tumor source, the 5-y survival rate is less than 10% in patients with unresectable liver metastases.…”

Section: Introductionmentioning

confidence: 99%

Novel mouse models of hepatic artery infusion

Kim

Fisher

Powers

et al. 2017

Journal of Surgical Research

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Clinicopathological characteristics, diagnosis and treatment of melanoma in Serbia: The Melanoma Focus Study

Cited by 3 publications

References 8 publications

Clinicopathologic characteristics of cutaneous melanoma - A single-center retrospective study

Clinicopathologic characteristics of cutaneous melanoma - A single-center retrospective study

Ultraviolet radiation exposure among Belgrade high school students: analysis of knowledge, attitudes and behaviour

Novel mouse models of hepatic artery infusion

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