Clinicopathologic Conference

Lw, Diggs; Rs, Jones

doi:10.1093/ajcp/22.12.1194

Cited by 14 publications

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“…To the best of our knowledge, only 12 patients are reported in English language publications with stroke attributed to sickle cell trait. [1][2][3][4][5][6][7][8] Stroke occurs with increased frequency in the younger age group in Afro-Asian countries9 and no definite cause to explain this phenomenon is found in the majority. '°People with sickle cell trait are usually asymptomatic and confirmation of the diagnosis requires detection of sickling and haemoglobin electrophoresis."…”

Section: Introductionmentioning

confidence: 99%

Sickle cell trait and stroke in the young adult

Radhakrishnan

Thacker

Maloo

et al. 1990

Postgraduate Medical Journal

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Summary: Two young patients with sickle cell trait (AS haemaglobinopathy) and ischaemic stroke are reported. The stroke involved the internal carotid artery territory in one and the brainstem in the other. A review of the literature is presented to suggest that the association of sickle cell trait and cerebral infarction is more than coincidental. Haemoglobin electrophoresis should be undertaken routinely in young subjects with ischaemic stroke.

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Section: Introductionmentioning

confidence: 99%

Sickle cell trait and stroke in the young adult

Radhakrishnan

Thacker

Maloo

et al. 1990

Postgraduate Medical Journal

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Bilateral Central Retinal Artery Occlusion

Kabakow¹

1955

AMA Arch Ophthalmol

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Cerebral infarction in sickle cell trait

Greenberg

Massey

1985

Annals of Neurology

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Sickle cell disease is known to predispose patients to the risk of cerebral infarction. However, only scattered reports exist of the neurological sequelae of the sickle cell trait. Only 8 cases are reported in the English literature, in some of which the sickle cell trait was not documented by hemoglobin electrophoresis. This report describes 2 men, age 35 and 24 years, who developed acute cerebral infarction. Investigation revealed no apparent cause for the lesion other than the sickle cell trait.

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Clinicopathologic Conference

Cited by 14 publications

References 0 publications

Sickle cell trait and stroke in the young adult

Sickle cell trait and stroke in the young adult

Bilateral Central Retinal Artery Occlusion

Cerebral infarction in sickle cell trait

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