Clinicomorphological Study Of Ovarian Lesions

Abstract

This prospective study was conducted at College of Medical Sciences-Teaching Hospital (CMS-TH) during December 2008 to May 2010. One hundred and fifty cases were analyzed. Age of the patients, parity, presenting symptoms, types of surgery, clinical diagnosis and complications were retrieved from case sheets. Surface epithelial tumors were more frequently observed above 30 years of age, (62.07%) cases. During 1st to 3rd decades of life, 62.8% germ cell tumors were seen; and sex cord tumors were seen in age group 41-60 years only. For all age groups, benign tumors were common than malignant tumors. There were 10.7% unmarried patients, 5.33% nulliparous, 35.55% of parity 1 to 2; 4% pregnant and 20 % postmenopausal women. There were 86.67% cases neoplastic, and 13.33% non-neoplastic ovarian lesions; 93.85% benign, 5.38% malignant and 0.77% borderline tumors. Surface epithelial tumors were the most common tumors (53.84%) followed by germ cell tumors (43.85%), constituted 46.7% and 38% among all ovarian lesions. The commonest benign tumors were serous cystadenomas and mature cystic teratomas, constituted 40% cases each. Dysgerminoma was the common malignant neoplasm (2.31%), all were seen in adolescents. Most of the other malignant neoplasms were observed above 40 years of age. Seventy percent (70%) of non-neoplastic lesions were hemorrhagic corpus luteum cysts. The commonest presenting symptom was pain in the lower abdomen (82%) followed by abdominal mass/ or distension (48.7%). Constitutional symptoms were observed in malignant cases only. Grossly, majority of the ovarian lesions were of size ranging 5 to 15 cm; and 89.93% cystic lesions. There were 48.7% lesions in the right ovary and 45.3% in the left ovary; 6% bilateral ovarian lesions, all of which were observed in benign and non-neoplastic lesions. The common complication observed was torsion (6.7%) followed by rupture of the cysts (6%).

Retrospective study of spectrum of ovarian tumours in a tertiary care setup

“…The present study had observed sex cord-stromal tumors in age group of 41 to 60 years which is similar to the study conducted by Maharjan et al [11] The present study constituted 5 cases (8%) of germ cell tumors out of 61 cases out of which one was malignant, 1 case of malignant germ cell tumor above the age of 50years. Benign germ cell were between 21 to 40years of age.…”

“…Of all malignant ovarian neoplasms, the most common were surface epithelial tumors, which were lower in the study done in Nepal by Maharajan et al, [11] where the most common malignant neoplasms were germ cell tumors. Similar to the study by Vaidya et al , [12] in which malignant surface epithelial tumor was observed above the age of 50 years, the present study had noticed a case of malignant surface epithelial tumor in a patient above the age of 50 years.…”

“…[12] The current study shows 3 cases of sex cord-stromal tumors between 41 and 60 years of age. Likewise the study conducted by Maharjan et al, [11] also shows sex cordstromal tumors between 41 and 60 years of age This current study shows various clinical presentations of ovarian tumors. Many patients experienced more than one symptom which is similar to study conducted by Kayastha et al [13] The most common symptom was abdominal pain (32 cases -52.4%), followed by abdominal mass (6 cases-9.8%).…”

“…This result is comparable with the study conducted by Bhattacharya et al , [9] in India were they noticed bilaterality was seen more common among malignant tumors. But the study conducted by Maharjan et al, [11] shows most bilaterality was observed in the benign tumors.…”

Histopathologic spectrum of cystic ovarian masses

“…The corpus luteal cyst was found as the most common cystic lesion in the study of Maharjan 9 and Zaman et al 14 .…”