Clinico- pathological profile of patients with breast diseases

Abstract

BackgroundTo evaluate the spectrum of breast diseases and their association with presenting complains of patients.MethodologyIt was a cross sectional study conducted from 1st January 2010 – 30th December 2012. A total of 254 breast specimens of patients, who were admitted in Civil Hospital Karachi with breast complaints, were included. Specimens were collected either from mastectomy, lumpectomy or needle biopsy from the admitted patients. Informed written consent was taken from all the patients. All patients with primary breast diseases were included. Patients undergoing chemotherapy or with secondary breast disease and slides with insufficient specimen were excluded. All data was entered and analyzed through SPSS 19.ResultThere were 254 breast lesions, histologically diagnosed in 3 year review period. The overall mean age of patients with breast lesion was 25.18, SD ± 11.73 with a wide age range of 12–74 years. Most common cases identified are benign 191(75.3%), followed by inflammatory 30(11.8%) and malignant lesions 30(11.8%). Most patients presenting with the complain of pain have diagnosis of fibroadenoma 24 (63.2%) while patient with complain of lump also have the most common diagnosis of fibroadenoma 147 (72.8%).ConclusionsStudy shows that in Pakistani females, mostly encountered breast lesion was fibroadenoma. Due to lack of awareness breast diseases present lately. Awareness must be created among women to reduce the mortality and morbidity with breast lesions.Virtual slidesThe virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1037059088969395.

Pathological Profile of Patients with Breast Diseases in Shiraz

“…In the present study, two mastitis cases (0.3%) were granulomatous and both were detected in non-menopausal women. These findings were in accordance with other previous studies (Tiwari and Tiwari;Aslam et al, 2013).…”

“…in different societies. According to the current study results, ductal carcinoma was the most prevalent malignancy during menopause, which is in agreement with the results of the previous studies (Ballard-Barbash, 1994;Franceschi et al, 1996;La Vecchia et al, 1997;Hussain et al, 2005;Aslam et al, 2013). Moreover, the total number of malignant masses was higher among the menopausal women compared to those in the reproductive ages, which is similar to the results obtained by Mehrabani et al (Mehrabani et al, 2012).…”

Clinicopathologic study of breast lumps in Abakaliki, South Eastern Nigeria

“…5,10 The vast majority of referred patients with breast disorders present with breast lumps and receive benign diagnosis when subjected to histopathology examination. 7,8,[10][11][12] Clinicopathologic study of breast lumps in Abakaliki,…”

A retrospective study of gynecomastia in male patients referred to Hatyai Hospital with breast lesions

“…It was lower than that in Italy (66.07%) [15], USA (67.3%) [16], UK (74.4%) [5], Spain (80.4%) [7], South Africa (82.7%) [8], and India (84.3%) [9]. A high prevalence of gynecomastia was also reported from Turkey (100%) [10], and Pakistan (100%) [11]. Male patients with gynecomastia often become anxious and seek medical attention.…”

“…The majority of male patients with gynecomastia are asymptomatic and referred for persistently tender breasts, palpable lump, or disturbed body image [5]. Previous studies reported that new cases of gynecomastia accounted for up to 80% of male patients referred to hospitals with breast lesions [6][7][8][9][10][11]. The aim of this study was to examine the nature of male breast lesions, especially those diagnosed as gynecomastia at Hatyai Hospital over the past 8 years (2004−2011).…”