Clinico-Pathological Findings of Bangladeshi Covid 19 Patients with their Clinical Outcome: Study of A Cohort of 201 Cases

Ahmed, Nasir; Islam, Akm Monwarul; Kabir, Amin Lutful; Rahman, Habibur; Sadat, SM Anwar

doi:10.3329/jbcps.v38i0.47346

Cited by 12 publications

(23 citation statements)

References 21 publications

(25 reference statements)

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“…Presenting symptoms in our population were fever, cough, headache, myalgia, sore throat, malaise, and respiratory distress similar to all affected countries in the world (Ahmed et al, 2020. Experience from recent pandemics of severe acute respiratory syndrome (SARS) and the Middle East respiratory syndrome (MERS) virus points to potential long-term sequelae of COVID-19 that we might have to deal with in near future (Fraser, 2021). Several studies have already suggested that COVID-19 might not only leave a scar in the lung but also have a wide range of sequelae involving the cardiovascular and neuro-psychiatric system (Vindegaard and Benros, 2020), (Ojha et al, 2020).…”

Section: Introductionsupporting

confidence: 58%

Section: Introductionmentioning

confidence: 81%

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Assessment of Post SARS CoV 2 Fatigue among Physicians Working in COVID Designated Hospitals in Dhaka, Bangladesh

Atmh

Ms²,

Khan

et al. 2021

Preprint

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Background: Fatigue has been observed after a number of infectious disease outbreaks around the world. After the outbreak of SARS CoV-2 in Wuhan, China in 2019, the disease turned into a pandemic very rapidly. Mental health is a key issue associated with such outbreaks. To explore the fatigue level among physicians working in designated public and private hospitals in Bangladesh, we conducted a matched case-control study of post-SARS-CoV-2 fatigue. Method: In this study 105 physicians who were diagnosed as COVID-19 infected, got treatment, and declared cured at least 6 weeks before the interview date, were recruited as cases and the same number of age and designation matched healthy physicians as control who are working in the same hospital. Case and control were selected in 1:1 ratio from each of the hospitals. The study population was selected by inclusion and exclusion criteria after taking informed written consent. Data collection was done by a semi-structured questionnaire. Diagnosis of COVID--19 infection was done by detection of SARS CoV-2 antigen by RT-PCR from reference laboratories in Bangladesh or by HRCT Chest. Result: Around two-thirds of the physicians were male (67.6% versus 32.4%). Most of them aged less than forty years (80.5%). The cases had a greater number of comorbid conditions than those who were negative. The FSS score (mean) was much higher for cases (36.7 with standard deviation of 5.3 versus 19.3 standard deviation of 3.8) than the control group with a statistically significant difference with no significant gender differentiation. Similarly, around 67.7% of the previously COVID positive physicians represented in the highest FSS score tertile compared to the respondents in the control group had a mean score of less than 3. The difference was also highly significant. Conclusion: Physicians, who had a previous history of COVID-19 infection had a higher total and mean FSS score, signifying a more severe level of fatigue than the physicians who had never been COVID-19 positive while working in the same hospital irrespective of their age and sex.

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Section: Introductionsupporting

confidence: 58%

Section: Introductionmentioning

confidence: 81%

Assessment of Post SARS CoV 2 Fatigue among Physicians Working in COVID Designated Hospitals in Dhaka, Bangladesh

Atmh

Ms²,

Khan

et al. 2021

Preprint

View full text Add to dashboard Cite

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“…Similarly, in other studies conducted in Bangladesh and other countries, HTN and DM were found to be the two most common comorbidities among patients. 9,[17][18][19] In present study, Death rate was 2%. This is consistent with the finding of other study conducted in Bangladesh observed that 1% death in their study.…”

Section: Discussionsupporting

confidence: 41%

Socio-demographic and Clinical Profile of Bangladeshi COVID 19 Patients with their Clinical Outcome in National Institute of Cardiovascular Diseases, Dhaka

Jahan

Bhuya

et al. 2021

Cardiovasc. j.

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Background: The novel corona virus (COVID 19) pandemic is a major global health threat of the twenty-first century. Clinical presentation, rapid identification of causes and isolation are vital for containments of rapidly spreading disease. The objective of the study was to report early findings on demographic profile, clinical presentation of the confirmed COVID 19 patients with their clinical outcome. Methods: This observational study was conducted in Microbiology Department of National Institute of Cardiovascular Diseases (NICVD) for the period of October 01, 2020 to November 30, 2020. Total 300 positive COVID 19 patients were included and interviewed. Informed written consent was ensured before participation. After collection, Data were analyzed to show the characteristics of COVID 19 cases and their clinical outcome after treatment. Results: Among the 300 cases 228 (76%) patients were male and 72 (24%) patients were female. Average age of the patients was 39 years. The most commonly observed symptoms were fever (70%), followed by cough (55%), breathlessness (42%), dysgeusia (38%), anosmia (25%). Respiratory symptom was the dominant feature of clinical presentation. The most prevalent affected age groups were 114 (38%) patients in 41-50 years age, 102 (34%) patients in 31- 40 years age. Among the total cases 255 (85%) patients were Urban residents and 234 (78%) had contact history. Among 300 patients 102 (34%) patients had co-morbidities and presence of co-morbidities (p<0.01) were significantly associated with mortality. The death rate was 2%. Conclusion: Typical presentations of COVID-19 were fever, cough, breathlessness, dysgeusia and anosmia. Requirement of ICU was 6% and overall mortality was 2% which was associated with comorbidities. Cardiovasc j 2021; 14(1): 50-54

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“…Another study of 100 COVID-19 patients demonstrated symptoms like rhinitis (13.0%), body ache (13%), headache (12.0%), sputum (7.0%), abdominal pain (4.0%), and hemoptysis (3.0%) [45]. A cohort study of 201 patients showed that very few patients were manifested with rare symptoms like burning body (1%), toothache (1%), itchiness (0.5%), red-eye (0.5%), oral ulcer (0.5%), and constipation (0.5%) and 4.5% were asymptomatic [46]. Hypertension (34.0%) was the most prevalent comorbidities associated with the patients followed by diabetes mellitus (21.4%).…”

Section: Clinical Features Of Covid-19 Among Bangladeshi Patientsmentioning

confidence: 99%

A review of the genome, epidemiology, clinical features, prevention, and treatment scenario of COVID-19: Bangladesh aspects

Noman¹,

Islam²,

Sana

et al. 2021

Egypt J Bronchol

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Background The ongoing acute respiratory disease pandemic termed COVID-19 caused by a newly emerged coronavirus has jeopardized the world’s health and economic sectors. As of 20 July 2020, the virus now known as SARS-CoV-2 has already infected more than 14 million individuals and killed 612,815 patients with a mortality rate of 4.12% around the world regardless of age, gender, and race. Main body Bangladesh has become one of its worst sufferers, with 207,453 infected people and 2668 related deaths with a mortality rate of 1.29% until 20 July 2020. More than 50% of COVID-19 patients in Bangladesh are aged between 21 and 40, but elderly people aged more than 60 have the highest mortality rate (44.7%). Male individuals are also more susceptible to the virus than females and consist of 71% and 79% among the infected and deceased patients, respectively. The most prevalent clinical features following the virus incubation period are fever, fatigue, and dry cough. A phylogenetic analysis study elucidated that the virus strain found in the country has 9 single-nucleotide variants, mostly in the ORF1ab gene, and a sequence containing 3 successive variants in the N protein, which reflects a weaker strain of SARS-CoV-2, implicating a possibility of its lower mortality rate. Another investigation of 184 genome samples of SARS-CoV-2 across the country implicated a close homology with a European haplotype of SARS-CoV-2. The country has also joined the race of vaccine development and started phase III clinical trials of a candidate vaccine developed by Sinovac Research and Development Co Ltd, China. Conclusion Bangladesh, as a developing country, still struggles with the pandemic and needs to scale up its response operation and improve healthcare facilities such as testing capacity, institutional quarantine, and isolation centers and promote awareness. Preventive measures such as strict lockdown, social distancing, and boosting the existing immune system are thus considered the only contrivances.

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Clinico-Pathological Findings of Bangladeshi Covid 19 Patients with their Clinical Outcome: Study of A Cohort of 201 Cases

Cited by 12 publications

References 21 publications

Assessment of Post SARS CoV 2 Fatigue among Physicians Working in COVID Designated Hospitals in Dhaka, Bangladesh

Assessment of Post SARS CoV 2 Fatigue among Physicians Working in COVID Designated Hospitals in Dhaka, Bangladesh

Socio-demographic and Clinical Profile of Bangladeshi COVID 19 Patients with their Clinical Outcome in National Institute of Cardiovascular Diseases, Dhaka

A review of the genome, epidemiology, clinical features, prevention, and treatment scenario of COVID-19: Bangladesh aspects

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