Clinico-pathologic findings in patients with median arcuate ligament syndrome (celiac artery compression syndrome)

Chaum, Manita; Shouhed, Daniel; Kim, Stacey; Walts, Ann E.; Marchevsky, Alberto M.

doi:10.1016/j.anndiagpath.2021.151732

Cited by 18 publications

(14 citation statements)

References 73 publications

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“…Let us note that patients with CACS are mostly asymptomatic. In symptomatic cases, postprandial abdominal pain, nausea, vomiting, diarrhea, loss of appetite, and abdominal discomfort are common (Aldahhas et al, 2021;Chaum et al 2021). Therefore, CACS is easily misdiagnosed as dyspepsia or peptic ulcer disease.…”

Section: Resultsmentioning

confidence: 99%

Celiac artery compression syndrome in children

Andreev¹,

Krasnov

Никитина³

et al. 2022

ijhs

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The manifestation of celiac artery compression syndrome in childhood is rarely described. At the same time, celiac artery compression syndrome remains one of the most discussed vascular diseases due to an unclear pathophysiological mechanism, difficulties in differential diagnosis, and the lack of a generally accepted algorithm for treating patients. In connection with the above, it seems relevant to analyze the features of managing children with celiac artery compression syndrome. As a result of the analysis of the scientific literature, we have come to the following conclusions: 1. Typical clinical characteristics of celiac artery compression syndrome include abdominal pain, epigastric murmur and weight loss associated with compression of the celiac artery and possibly celiac ganglia by the median arcuate ligament. 2. CT angiography and conventional catheter angiography are the gold standard for diagnosis. However, imaging findings should not be interpreted in isolation from clinical manifestations. 3. Surgical decompression of the celiac artery by resection of the median arcuate ligament is the treatment of choice for this syndrome. Both open surgery and laparoscopic techniques are safely performed with minimal morbidity and mortality. Endovascular treatment of compression celiac stenosis may have limited success.

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Section: Resultsmentioning

confidence: 99%

Celiac artery compression syndrome in children

Andreev¹,

Krasnov

Никитина³

et al. 2022

ijhs

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“…Forty-six years later, Harjola reported celiac artery compression in a female patient presenting with unexplained abdominal pain, and afterward, several case reports continued to shed the light on this rare condition, which led to the understanding of the role of celiac artery compression in causing ischemic intestinal pain. However, the fact that this condition only affects about two per 100,000 population makes it an overlooked diagnosis [ 3 ]. Gut ischemic pain can present with postprandial abdominal pain, nausea, vomiting, and weight loss [ 2 ].…”

Section: Discussionmentioning

confidence: 99%

Celiac Artery Compression Syndrome as an Uncommon Cause of Intractable Postprandial Abdominal Pain: A Case Report

Mahgoub¹,

Abdelfattah²,

Dawoud³

et al. 2022

Cureus

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Celiac artery compression syndrome (CACS) is an uncommon and poorly understood condition. Compression of the celiac artery by the median arcuate ligament causes intractable postprandial abdominal pain, weight loss, vomiting, and nausea. We present a case of a 68-year-old male who suffered recurrent severe episodes of postprandial abdominal pain associated with occasional nausea, vomiting, and elevated blood pressure. The diagnostic workup was significant for celiac artery compression on computed tomography angiography. Diagnosis of CACS was made after the exclusion of the other possible pathologies, and the patient was referred to the surgical team for further management for median arcuate ligament release on an elective basis.

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“…The fact, however, that these patients received a comprehensive and time consuming evaluation and work-up makes it likely that symptoms were present for more than three months. 1,6,11,13,14,19,[22][23][24][25][26][27][28][29][30][31][32][33] In one study, symptom relief after treatment suggested that patients were symptomatic although it was not clearly stated that patients indeed had abdominal symptoms at the time of inclusion. 34 Based on these considerations we included these studies in the present review.…”

Section: Adult Cohortmentioning

confidence: 99%

“…In nine studies including 274 patients, postintervention CA patency was determined with Duplex, CTa or MRa. 6,15,26,[42][43][44][45]49,52 In 212 patients (77%) a patent CA was established.…”

Section: Adult Cohortmentioning

confidence: 99%