Clinico histopathological correlation within the spectrum of hansen's disease: A multicentric study in North India

Mohan, Nitesh; Mishra, Nitin

doi:10.5958/j.2319-5886.2.4.142

Cited by 7 publications

(6 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…12 In similar studies done by Mitra et al, Francisco VargasOcampo et al and Nitesh Mohan et al, the overall correlation was 53%, 42.9% and 56.4% respectively. 9,13,14 Thus, the concordance rate is in agreement with that of many similar studies.…”

Section: Discussionsupporting

confidence: 92%

A Study of Clinico-Pathological Concordance in Patients With Hansen’s Disease Across the Spectrum

Lakshmy¹,

K²,

Nandakumar³

et al. 2017

jemds

View full text Add to dashboard Cite

show abstract

Section: Discussionsupporting

confidence: 92%

A Study of Clinico-Pathological Concordance in Patients With Hansen’s Disease Across the Spectrum

Lakshmy¹,

K²,

Nandakumar³

et al. 2017

jemds

View full text Add to dashboard Cite

show abstract

“…In literature there are several studies were done to evaluate the correlation between clinical findings and histological features of leprosy. The various concordance rates noted in these studies were 56.54% (Nitesh Mohan et al, 2013) 16 , 62.9% (Kumar et al, 2014) 17 , 57.3% (Bajjaragi et al, 2013) 18 , 61.8% (Nadia et al, 2015) 19 , 65% (K L Shobha et al, 2015) 20 . From the above data it's evident that clinicohistopathological concordances of most of the studies are more or less similar to our study.…”

Section: Discussionmentioning

confidence: 91%

A Clinical and Histopathological Correlation among Leprosy Patients (in this Post Elimination Era) Attending Tertiary Referral Centre

Thombare

Kote

Gugle

et al. 2020

mvpjms

View full text Add to dashboard Cite

Background: Leprosy is caused by Mycobacterium leprae, which chiefly affect skin and peripheral nerves. Leprosy expresses itself in different clinicopathological forms depending upon underlying immunity of the host. Histopathology is considered gold standard for accurate diagnosis especially in early disease, however, clinicopathological correlation is a must for appropriate diagnosis and classification of disease that will in-turn affect the treatment and overall prognosis of the patient. The present study of clinicohistopathological correlation among leprosy patients in this post elimination era was undertaken. Aims and objectives: To study the clinical and histopathological correlation among leprosy patients. Materials and Methods: Present study consists of 54 patients of newly diagnosed leprosy cases at Department of Dermatology, Venerology and Leprology from November 2016 to October 2018. Skin punch biopsy and slit skin smear taken from patients. Histopathological examination by staining with H&E and Fite-Faraco stain for tissue AFB and Ziehl-Neelsen staining of SSS for presence of AFB. Results: In this study, 35 cases (64.81%) showed clinicohistopathological concordance and 19 cases (35.19 %) were discordant according to Ridley-Jopling spectrum. Conclusion: Histology should be performed in all suspected patients of leprosy if feasible, for exact allocation of the patient across the spectrum for accurate treatment and to identify the vulnerable patients in borderline spectrum as they are prone for reactions, neuritis and thus deformities and it also aids in achieving terminal goal of leprosy elimination.

show abstract

“…Though, the clinical diagnosis is based on characteristic skin lesions with sensory loss, a great variation are seen in interpretation of these lesions, both clinically and histopathologically. 8 Clinical classification gives recognition only to gross appearance of the lesion, whereas the parameters used for histopathological classification are well defined, precise and also take into account the immunological features. 1,9 Before confirming a case of Leprosy of particular type, the clinical features should be correlated and confirmed with histological examination along with bacteriological index.…”

Section: Resultsmentioning

confidence: 99%

Clinical Profile and Histopathological Correlation of Hansen’s Disease Among Patients Attending a Private Medical College Hospital in Tamilnadu- A Retrospective Study

Rajalakshmi¹,

Balasubramanian²,

Ramanathan³

2017

jemds

View full text Add to dashboard Cite

BACKGROUNDLeprosy is a treatable chronic infectious disease, prevalent in South East Asian countries, especially India. Skin biopsy is an important tool in diagnosing leprosy and determining the type of leprosy. Before labelling a patient as a case of leprosy and starting multidrug treatment for particular type, the clinical findings should be correlated and confirmed with histopathological examination and bacteriological index of skin biopsy.The objective of this study is to find out the clinical profile and histopathological correlation of Hansen's disease among patients attending a private medical college in Tamilnadu.

show abstract

Clinico histopathological correlation within the spectrum of hansen's disease: A multicentric study in North India

Cited by 7 publications

References 4 publications

A Study of Clinico-Pathological Concordance in Patients With Hansen’s Disease Across the Spectrum

A Study of Clinico-Pathological Concordance in Patients With Hansen’s Disease Across the Spectrum

A Clinical and Histopathological Correlation among Leprosy Patients (in this Post Elimination Era) Attending Tertiary Referral Centre

Clinical Profile and Histopathological Correlation of Hansen’s Disease Among Patients Attending a Private Medical College Hospital in Tamilnadu- A Retrospective Study

Contact Info

Product

Resources

About