Clinico-epidemiological study of dengue cases in a tertiary care hospital, Guwahati, Assam, India

Bhardwaj, Lalit Mohan; Borthakur, Swapnav; Bhattacharyya, P C

doi:10.18203/2349-3933.ijam20175175

Cited by 2 publications

(3 citation statements)

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“…Incidence of Dengue in Assam has been documented in many studies. [2][3][4][14][15][16][17][18] In our study we have seen that the Kamrup (Metro) district has reported the highest number of cases in all the years. An interesting finding of this study is the occurrence of Dengue in districts that were unaffected in previous years (Table 3) which can be attributed to increase in long-distance travel, population growth and urbanisation, lack of sanitation, ineffective mosquito control etc.…”

Section: Discussionmentioning

confidence: 98%

“…The disease is currently spreading to semi-urban areas of other districts of Assam supported by serological evidence for circulating dengue virus serotypes. 4 Dengue infection is usually confirmed by identification of viral genomic RNA, antigens, or the antibodies it elicits. Antigen detection tests based on NS1 detection have been designed to detect the dengue viral NS1 protein which gets released from the dengue infected cells and appears early in the 13-17.…”

Section: Introductionmentioning

confidence: 99%

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Seroprevalence of dengue cases in a tertiary care hospital

Dina¹,

Sarma²,

Parasmita³

et al. 2019

International Journal of Health Research and Medico Legal Practice

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Background: Dengue is a mosquito borne viral disease of global public health concern and is a major cause of morbidity in most of the endemic regions of the world. In northeast India, particularly Guwahati, Assam has been experiencing dengue every year with high morbidity since its first outbreak in 2010 and therefore emerging as major public health concern in northeast India and spreading with increased morbidity. Objective: To analyse the seroprevalence and epidemiological trend of dengue among patients presenting in Gauhati Medical College and Hospital from the year 2012 to 2017. Materials and methods: A retrospective study was done from the year 2012 to 2017 in blood samples received in the department of Microbiology, Gauhati Medical College & Hospital. Dengue NS1 antigen and Dengue IgM antibody ELISA tests were performed for the confirmation of dengue cases which was performed as per the manufacturer's guidelines. We estimated the incidence by applying age and sex distribution of Dengue cases in Assam. Results: From the six years study we found that the prevalence of Dengue was highest in 2012 (47%) and lowest in 2014 (10%). Highest sample load was seen in 2016. In all the years, males patients were more than the female patients. Commonest age-group of the affected patients was between 25-34 years of age. In Assam, Kamrup (Metro) district followed by Kamrup (Rural) showed highest case load in all the years. Conclusion: Dengue has remained a persistent problem in Assam with the increasing distribution range of Aedes aegypti. There is a need of identification of high-risk areas, vector incrimination and seasonal infectivity of dengue so that future outbreaks can be avoided by targeted

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Section: Discussionmentioning

confidence: 98%

Section: Introductionmentioning

confidence: 99%

Seroprevalence of dengue cases in a tertiary care hospital

Dina¹,

Sarma²,

Parasmita³

et al. 2019

International Journal of Health Research and Medico Legal Practice

View full text Add to dashboard Cite

show abstract

“…This study also reveals 8.9% had platelet count between 50,000 -1 lakh and 17.6% had between 1-2 lacs but in a study by Bhardwaj LM et al where 70.7% of dengue patients had platelet count below 1.5 lacs. About 34% of admitted dengue cases had platelet infusion but in the study by Bhardwaj LM et al only 5.69% required platelet transfusion and 3.25% required blood transfusion 18. Among different treatment modalities offered at the SCB Medical College, Hospital, Cuttack; 55.7% were treated with paracetamol and antibiotics only, 24.4% with paracetamol, antibiotics and antimalarial, 11.3% with paracetamol, antibiotics, antimalarial and platelet infusion.…”

mentioning

confidence: 95%

Clinical Profile of Dengue Fever at SCB Medical College and Hospital, Cuttack, Odisha

Bisoyi

Behera

Patnaik

et al. 2018

JCD

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Background: India is one of the seven identified countries in the South-East Asia region regularly reporting dengue fever outbreaks and epidemics and has transformed into a major niche for dengue infection with more new areas being struck by dengue epidemics like Odisha. The present study was aimed to assess clinical profile and current status of dengue cases admitted in Dengue ward of SCB Medical College hospital, Cuttack, Odisha.Methods: It was a cross sectional prospective observational hospital-based study between July to September 2016 in the Dengue ward of SCB Medical College Hospital, Cuttack, Odisha. Of 3600 dengue patients admitted at this hospital during the study period, a total of 720 cases were selected by systemic random sampling method. (20% of daily 40 new dengue cases). The clinical manifestations and laboratory findings of each group of illness were compared using Chi-square test.Results: Out of 720 dengue patients, 82.5% were Non-severe Dengue and only 17.5% were Severe Dengue. The Mean age of patients was 36±14.6 years with a male to female ratio of 4:4.1. However, bleeding manifestations like epistaxis, melena were seen in in 15.4% cases especially in severe dengue cases. Rash was present in 17.5% cases. 64 severe dengue cases had TPC less than 50, 000. Among different treatment protocols given to all these dengue patients, 55.7% of non-severe dengue cases were treated with paracetamol and antibiotics, whereas 38.9% of severe dengue cases were treated with paracetamol, antibiotics and platelet infusion. Only 5.7% of non-severe dengue cases were referred to ICU, whereas 50% of severe dengue cases were referred to ICU. Conclusion:The present study highlights the importance of dengue fever to the clinician in the area of epidemiology, its varied manifestations, complications, and outcome of the disease with no specific antiviral therapy or vaccination available in our country, mortality from dengue fever can only be prevented by its early diagnosis and timely management.

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Clinico-epidemiological study of dengue cases in a tertiary care hospital, Guwahati, Assam, India

Cited by 2 publications

References 10 publications

Seroprevalence of dengue cases in a tertiary care hospital

Seroprevalence of dengue cases in a tertiary care hospital

Clinical Profile of Dengue Fever at SCB Medical College and Hospital, Cuttack, Odisha

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