Clinico-epidemiological profile of Influenza A H1N1 cases at a tertiary care institute of Uttarakhand

Abstract

Introduction: The swine (H1N1) virus responsible for worldwide pandemics since 2009 is now causing seasonal epidemics. Since then alarming spikes of swine flu cases have been reported from Uttarakhand every year. There are limited studies conducted in this Himalayan belt to evaluate the clinical and epidemiological profile of the patients admitted in tertiary care hospitals. Aims & Objectives: This study aims to summarize the clinical and epidemiological attributes of swine flu and to approximate the burden of Influenza A H1N1 (Swine Flu) cases in this Himalayan belt. Material and Methods: Clinical and epidemiological characteristics of influenza A H1N1 cases from October 2018 to April 2019 were retrospectively and descriptively analyzed using data from the Medical Records Section and the isolation ward at Shri Guru Ram Rai Institute of Medical and Health Sciences; Shri Mahant Indiresh hospital. Results: A total of 1126 (51.6%) patients were tested of which 30% (338) patients were found to be H1N1 positive. Maximum cases and positivity were detected in the months of January (26.4%), February (50.3%), and March (14.8%), and the patients in the age groups of 41–50 (21.9%) and 51–60 years (19.3%) accounted for majority of the cases. The most common symptoms were fever (85.8%), cough (82.2%), sore throat (82%), and breathlessness (71.3%). A case fatality ratio of 10.9% was observed. A significant statistical association ( p value < 0.00001) was reported between co-morbid conditions and death. Conclusion: According to the results of this study, close caution should be exercised in case of patients infected with H1N1 particularly those with co-morbidities.

Perfil epidemiológico dos casos notificados de Influenza A H1N1 em Campinas – São Paulo

“…O vírus H1N1 pertence à família Orthomyxoviridae, que são vírus de RNA e incluem três subtipos de influenza A, B e C (SADAR et al, 2016). Em relação ao subtipo H1N1, as apresentações clínicas e características epidemiológicas dos pacientes podem apresentar diferenças em relação às diferentes localizações geográficas e diversos períodos de tempo (PANDITA et al, 2021). Indivíduos de todas as idades enquanto outros relataram apenas uma doença leve semelhante à gripe.…”