Clinico-epidemiological investigation of feline panleukopenia and parvoviral enteritis in the two largest pet hospitals in Bangladesh

Chisty, Nurun Nahar; Belgrad, Joseph P.; Sattar, Abdullah Al; Akter, Shirin; Hoque, Ahasanul

doi:10.5455/javar.2020.g474

Cited by 2 publications

(2 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The prevalence of FPL observed in our study was 23%, which is higher than the prevalence reported in a previous study [27]. However, our findings align with the results reported in studies [25,26]. The relatively higher prevalence observed in our study may be attributed to the sampling method employed.…”

Section: Plos Onesupporting

confidence: 79%

“…A recently published study reported a 18.37% prevalence of FPL from diarrheic cats in Bangladesh, while a previous study documented a 22.41% prevalence in the Tangail district. So far, only a single isolate has been molecularly characterized showing 99.71% homology with another FPLV isolate from the United Arab Emirates [25][26][27]. However, there is lack of reported epidemiological studies in Bangladesh that describe the risk factors for FPL in suspected cats, along with molecular characterization.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Epidemiology and molecular characterization of Feline panleukopenia virus from suspected domestic cats in selected Bangladesh regions

Kabir,

Habib,

Chouhan

et al. 2023

PLoS ONE

View full text Add to dashboard Cite

Feline panleukopenia (FPL) is a highly contagious cat disease and is endemic in Bangladesh. The study aims to describe the epidemiology and molecular characterization of the Feline panleukopenia virus from the suspected domestic cats in selected Bangladesh regions. Randomly, 161 rectal swabs were collected from the pet hospitals between July 2021 and December 2022. A structured questionnaire was administered through face-to-face interviews with cat owners in order to collect data on potential risk factors for FPL, such as age, sex, sharing litter boxes and every day utensils in multicat households, vaccination history, hospital visits for other diseases, and season. The rectal swabs were tested by PCR targeting the VP2 capsid protein gene, and six PCR-positive samples were further sequenced for molecular characterizations. The risk factors for FPLV were identified using multivariable logistic regression analysis. The overall prevalence of FPL among suspects was 22.9%. The mortality and case fatality were 10.6%, and 45.9%, respectively. However, mortality in kittens was significantly higher (16.4%) than younger cats. The odds of FPL were 8.83 times (95% CI: 3.14–24.85) higher among unvaccinated cats than vaccinated cats. The winter season had almost six times (95% CI: 1.38–24.40) higher odds of FPL than rainy season. In a multicat house, the odds of FPL was about five times (95% CI: 1.93–13.45) higher for cats that shared a litter box and food utensils compared to those that did not engage in such sharing. Visiting hospitals for other reasons nearly triples the odds of FPL (OR: 2.80, 95% CI: 1.04–7.54) compared to cats that do not visit hospitals. Analysis of partial sequence of the VP2 gene revealed genetic variations among the isolates from different regions. Among these isolates, four were identical to FPLV isolates from South Korea and China, while one showed complete homology with FPLV isolates from Thailand. In contrast, the remaining one was 100% identical to Carnivore protoparvovirus-1 isolated from a feline sample in Italy. Our isolates were classified into three distinct clades alongside Feline panleukopenia virus and Carnivore protoparvovirus-1. One in every three suspected cats was infected with Feline panleukopenia. Regular vaccination of the cats, especially those that share common litter box and food utensils and visit hospitals for other purposes, will help reduce the prevalence of FPL in Bangladesh. Besides, it is worth emphasizing the existence of genetic diversity among the circulating Feline panleukopenia viruses in Bangladesh.

show abstract

Section: Plos Onesupporting

confidence: 79%

Section: Introductionmentioning

confidence: 99%

Epidemiology and molecular characterization of Feline panleukopenia virus from suspected domestic cats in selected Bangladesh regions

Kabir,

Habib,

Chouhan

et al. 2023

PLoS ONE

View full text Add to dashboard Cite

show abstract

Prevalence and Associated Risk Factors of Canine Parvovirus and Canine Influenza Virus Infections in Pet Dogs in Dhaka District of Bangladesh

Bhattacharjee¹,

Rahman²,

Sarker³

et al. 2021

JVMOHR

View full text Add to dashboard Cite

Background: There are approximately 1.6 million dogs in Bangladesh and almost 83% of these dogs live on the street and accordingly 17.0% dog population are kept as pet mostly in the metropolitan cities with major population in Dhaka, Chottogram and Sylhet in Bangladesh. Some promiscuous research findings on Canine parvovirus enteritis (PVE) and Canine influenza virus (CIV) have been reported in inland literature. Objective: To determine the prevalence and associated risk factors of canine parvovirus and canine influenza virus infections in dogs supported with brief review for future direction of research and prevention Materials and Methods: A cross sectional study was conducted on total of 173 pet dogs for the prevalence of CIV and 70 dogs for CPV infections of different breed, age and gender by collecting nasal swab samples for CIV and rectal swabs for CPV infection. Each of the collected nasal swabs was tested by RapiGen Canine influenza Ag test kit and rectal swab samples with RapiGen Canine parvovirus Ag test kit (RapiGen INC., South Korea, 2012). Chi-square test was used detect the significance of risk factors of the infections in dogs. Results: All the 173 nasal swabs of pet dogs collected from different thanas of the Dhaka district showed negative with RapiGen CIV Ag test kit test. Out of four published reports on the prevalence of CIV infection in dogs, of which two reports showed 10.71 to 13.33% prevalence rate of CIV whereas two reports (including this one) showed negative result with the same test. An overall 7.14% prevalence of CPV infection in pet dogs was recorded in this study. The prevalence of CPV in relation to breed was found 22.22% in German shepherd and 2.86% in Labrador whereas local, Bull mastiff and Samoyed breeds found negative for CPV infection. The higher prevalence of CPV infection was recorded in puppies up to six months of age (14.81%) than in growing dogs aged between >6 to 12 months (7.14%) whereas adult (>1 to 2 years) and older (> 2 years) dogs found negative to this infection. Comparatively higher prevalence of CPV infection was detected in male (8.33%) than in female (5.88%) dogs. No CPV infection was recorded in vaccinated dogs, whereas 19.23% unvaccinated dogs affected with this infection. All the rectal swab samples of apparently healthy dogs (no sign of diarrhea) showed negative to CPV infection, whereas 25.0% dogs with diarrhea sign found positive to CPV infection. Review of inland literature reveals that out of nine articles published on CPV infection of which RapiGen CPV Ag test kit has been used in four, PCR in one and clinical method of diagnosis in four articles, whereas only RapiGen CIV Ag test kit has been used for the diagnosis of CIV infection. Conclusion: The prevalence of CPE associated with diarrhea in 7.14% pet dogs has been recognized in this investigation with supports of earlier reports whereas the prevalence of CIV in pet dogs varied widely from negative to 13.33% prevalence in dogs. Age and vaccination of dogs have been recognized as primary risk factors which should be considered in planning a control program whereas others factors like breeds, season, geographical areas can be considered as secondary risk factors varied widely in different reports and countries. Comparative evaluation of different diagnostic tests to find out the ‘gold standard’ and vaccination against CPI in puppies may be suggested to control this disease in dogs. Keywords: Prevalence, Risk factors, CIV, CPV, Dogs, Breeds, Dhaka district, RapiGen Ag test kit, Brief review

show abstract

Clinico-epidemiological investigation of feline panleukopenia and parvoviral enteritis in the two largest pet hospitals in Bangladesh

Cited by 2 publications

References 14 publications

Epidemiology and molecular characterization of Feline panleukopenia virus from suspected domestic cats in selected Bangladesh regions

Epidemiology and molecular characterization of Feline panleukopenia virus from suspected domestic cats in selected Bangladesh regions

Prevalence and Associated Risk Factors of Canine Parvovirus and Canine Influenza Virus Infections in Pet Dogs in Dhaka District of Bangladesh

Contact Info

Product

Resources

About