Clinico-Biological Evolution of Hyperthyroid Goiters After Total Thyroidectomy in The Department of Endocrinology-Internal Medicine at Mali Hospital, Bamako, Mali

Abstract

Introduction: Clinical and biological manifestations after total thyroidectomy constitute one of the frequent reasons for consultation in our medical services. Several studies on thyroid pathology have been carried out in Mali, but none to our knowledge has been devoted to the postoperative clinical and biological follow-up of hyperthyroid goitres after total thyroidectomy, hence the interest of this study which aimed to evaluate the clinico-biological manifestations after total thyroidectomy of hyperthyroid goitres in the department of Endocrinology-Internal Medicine, Surgery of the Hospital of Mali. Materials and methods: This was a descriptive, retrospective study from January 2010 to December 2014. All patients who had undergone total thyroidectomy for hyperthyroid goiter, who were treated before discharge with levothyrox (50 to 150 µg/day) to prevent hypothyroidism, who had a complete file and who were followed up in the Endocrinology-Internal Medicine and Thoracic Surgery Departments of the Mali Hospital were included. Results: We collected 550 cases, of which 54 met our inclusion criteria, i.e. a prevalence of 9.8%. The series was composed of 51 (94.4%) women and 3 (5.6%) men, i.e. a sex ratio of 0.06. The most common age range was 41-60 years with extremes of 22 and 75 years. Anterocervical swelling was the reason for consultation in 98.1% of cases. At D7 post-op, we noted dysphonia in 10 (18.5%) patients, 5 (9.25%) cases of hypocalcemia and 33 (61.1%) cases of hypothyroidism on 38 samples. The other manifestations were: at 1 month follow-up, asthenia (5.6%), biological hypothyroidism (9.3%), at 3 months follow-up: transient hypoparathyroidism (3.7%), a loss of sight rate (7.4%), at 6 months follow-up: signs recorded were asthenia, fragility of the phaneras, lethargy, a loss rate of 11.1%. At one year follow-up, the most frequent signs were: skin infiltration (3.7%), definitive hypoparathyroidism (3.7%), a loss rate of 16.7%. Conclusion: Total .............