Clinico-bacteriological profile of spontaneous bacterial peritonitis in cirrhosis of liver with ascites

Goel, Shewtank; Pandey, Pooja Tripathi; Kumar, Abhay; Kumar, Nidhish; Arora, Deval; Singh, Abhishek

doi:10.18203/2320-6012.ijrms20194622

Cited by 2 publications

(2 citation statements)

References 12 publications

(12 reference statements)

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“…35.5% in another study in Assuit [36] and 41.7% in Tanta [37]. The prevalence of SBP in the current study was higher than that reported in a global study on 1,302 patients from Asia, Europe and America which was 27% [10] and that reported in two different Indian studies as it was 38.09% [38] and 16.12% [39]. This difference may be attributed to the difference in samples' size, the mean age and the type of studied patients (whether inpatients or outpatients, symptomatic or asymptomatic), the wide use of PPI in the present study (73%) which may be a risk factor for SBP [40] [42].…”

Section: Discussioncontrasting

confidence: 65%

Bacteriological Profile and Antimicrobial Resistance in Ascitic Fluid of Patients with Community Acquired and Nosocomial Spontaneous Bacterial Peritonitis

Abdel-Salam

Zeinelabedin

Abdelrahman

et al. 2022

Benha Medical Journal

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Background: Spontaneous bacterial peritonitis is the most frequent infection complicating liver cirrhosis. Recent changes in bacterial ecology and emerging antibiotic resistance have resulted in failure to respond to empirical therapy with 3 rd generation cephalosporin in 33%-75% of cases and such failure is associated with reduced survival. Aim of the work: To identify the causative bacteria of community acquired and nosocomial SBP and their antimicrobial resistance patterns in an attempt to perform a local bacteriological surveillance to optimize empirical treatment. Patients and methods: Three hundred patients with ascites due to liver cirrhosis were enrolled in this study. All patients were subjected to history taking, clinical examination, ascitic fluid analysis, culture and ultrasonography. SBP was diagnosed by ascitic PNL ≥250/mm 3 .Results: One hundred and eighty-five patients (61.7%) were diagnosed as SBP. Community acquired SBP (83.8%) was more common than nosocomial SBP (16.2%). One hundred and forty patients (75.7%) had culture positive, and 45 patients (24.3%) had culture negative SBP. Gram positive (G+) cocci (64.3%) were more common than Gram negative (G-) bacilli (35.7%). Among culture positive cases, 110 patients had community-acquired and 30 patients had nosocomial SBP. The overall cefotaxime resistance was 44.4%; being higher in nosocomial (100%) than community acquired group (37.5%). No resistance to ampicillin/salbactam, piperacillin/tazobactam, vancomycin, linezolid, meropenem or tigecyclin was identified. Conclusion: There is an emerging pattern towards G+ bacteria and 3 rd generation cephalosporins resistance in the

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Section: Discussioncontrasting

confidence: 65%

Bacteriological Profile and Antimicrobial Resistance in Ascitic Fluid of Patients with Community Acquired and Nosocomial Spontaneous Bacterial Peritonitis

Abdel-Salam

Zeinelabedin

Abdelrahman

et al. 2022

Benha Medical Journal

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“…Diagnostic paracentesis should always be performed for all cases of ascites, irrespective of cause [15]. A microbiological study by means of ascitic fluid culture and antibiotic susceptibility testing should also be performed to find out the causative organism and its sensitivity pattern in cases of infected ascites and thereby improve the prognosis of patients.…”

Section: Discussionmentioning

confidence: 99%

A Study on the Bacteriological Profile of Ascitic Fluids and Their Antibiotic Susceptibility Pattern in a Tertiary Care Hospital

Pachiyappan,

Sethuraman

2023

Cureus

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BackgroundAscitic fluid culture remains an essential step in the management of all patients with ascites, regardless of their presenting complaints. Diagnostic paracentesis should not be delayed or prevent timely administration of antibiotics, particularly in unstable patients. Hence, it is an essential part of the surveillance system of every hospital to perform ascitic fluid culture and assess the antibiotic susceptibility patterns of bacterial isolates.

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Clinico-bacteriological profile of spontaneous bacterial peritonitis in cirrhosis of liver with ascites

Cited by 2 publications

References 12 publications

Bacteriological Profile and Antimicrobial Resistance in Ascitic Fluid of Patients with Community Acquired and Nosocomial Spontaneous Bacterial Peritonitis

Bacteriological Profile and Antimicrobial Resistance in Ascitic Fluid of Patients with Community Acquired and Nosocomial Spontaneous Bacterial Peritonitis

A Study on the Bacteriological Profile of Ascitic Fluids and Their Antibiotic Susceptibility Pattern in a Tertiary Care Hospital

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