Clinician-Assisted Internet-Based Treatment is Effective for Depression: Randomized Controlled Trial

Abstract

These results replicate those from the pilot trial reported by Perini et al. and are consistent with literature indicating that Internet-based programmes for depression and other mental disorders combined with clinical guidance can result in clinically significant improvements. These data provide further support for the development of Internet-based treatment for common mental disorders.

Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) collaborative update of CANMAT guidelines for the management of patients with bipolar disorder: update 2013

“…The availability of internet-based strategies has grown substantially, with demonstrated efficacy in reducing depressive symptoms and improving psychological quality of life (24)(25)(26)(27). The acutely manic bipolar patient may present in an agitated state that acts as a barrier to therapy, interrupts the physician-patient alliance, and creates a disruptive, even hazardous, environment.…”

Transdiagnostic internet treatment for anxiety and depression = Tratamiento transdiagnóstico por internet de la ansiedad y la depresión

“…Prior to developing TD iPT, we developed and evaluated disorder-specifi c iPT interventions to treat social phobia Titov, Andrews, Choi, Schwencke, & Mahoney, 2008;Titov, Andrews, Schwencke, et al, 2010;, PD (Wims et al, 2010), GAD , and depression (Perini et al, 2009;Titov, Andrews, Davies, et al, 2010). These interventions were evaluated in 12 RCTs and 3 open trials with participants who met a principal DSM-IV diagnosis for the relevant disorder.…”

“…A substantial number of trials have reported the effectiveness of disorder-specifi c iPT at treating several common mental disorders. For example, more than 10 randomised controlled trials (RCTs) have reported the clinical benefi ts of iPT for clinical and subclinical depression Perini, Titov, & Andrews, 2009;Ruwaard et al, 2009;Titov, Andrews, Davies, et al, 2010), social phobia (Andersson et al, 2006;Berger, Hohl, & Caspar, 2009;Botella et al, 2010;Carlbring et al, 2007;, and panic disorder Klein et al, 2009;Wims, Titov, Andrews, & Choi, 2010). Encouraging evidence has also been found from a smaller but rapidly growing number of RCTs or open trials evaluating iPT for generalised anxiety disorder Robinson et al, 2010;, obsessive compulsive disorder Andersson et al, 2012;Wootton et al, 2011), and post-traumatic stress disorder (Klein et al, 2010;Spence et al, 2011).…”

Internet Cognitive–Behavioral Therapy for Depression in Older Adults With Knee Osteoarthritis: A Randomized Controlled Trial

“…The iCBT Sadness Program consists of 6 online lessons representing best practice CBT, as well as regular homework assignments and access to supplementary resources. The Sadness Program has been validated in a number of clinical efficacy and effectiveness trials (28,(32)(33)(34)(35). Each lesson comprises a cartoon narrative in which a character gains mastery over MDD symptoms by learning and implementing CBT skills.…”

“…Given the growing burden of OA and depression, the lack of people accessing depression treatment, and the interference of depression with OA treatment outcomes in this population, we investigated the effects of a validated iCBT program for depression (the Sadness Program [28]) in older adults with OA and comorbid depression. To our knowledge, no randomized trial has assessed the effects of an iCBT program for depression in this target population.…”