Clinically related or predictive factors and impacts on long-term treatment outcomes of involvement behaviors in patients with obsessive–compulsive disorder

Yanagisawa, Yoshinobu; Matsuura, Naomi; Mukai, Keiichiro; Nakajima, Ayako; Motoyama, Mikuni; Yamanishi, Kyosuke; Hayashida, Kazuhisa; Matsunaga, Hisato

doi:10.1016/j.comppsych.2015.03.002

Cited by 10 publications

(9 citation statements)

References 32 publications

(59 reference statements)

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“…The current results suggest that the presence of IB, along with lower GAF scores at initial assessments, are particularly strong significant predictors of poor response. This replicates our previous finding that the presence of IB or hoarding symptoms was associated with poorer short‐term (<1 year) outcomes in OCD . Another study found that elevated ASD traits also tended to negatively influence 1‐year outcomes in OCD .…”

Section: Discussionsupporting

confidence: 89%

“…This replicates our previous finding that the presence of IB or hoarding symptoms was associated with poorer short-term (<1 year) outcomes in OCD. 19,26 Another study found that elevated ASD traits also tended to negatively influence 1-year outcomes in OCD. 36 These findings raise the possibility that psychopathological features, social and interpersonal functioning, and psychosocial background may have important impacts on outcomes in OCD.…”

Section: Discussionmentioning

confidence: 99%

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Ten‐year follow‐up study of Japanese patients with obsessive–compulsive disorder

Nakajima

Matsuura

Mukai

et al. 2018

Psychiatry Clin Neurosci

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Section: Discussionsupporting

confidence: 89%

Section: Discussionmentioning

confidence: 99%

Ten‐year follow‐up study of Japanese patients with obsessive–compulsive disorder

Nakajima

Matsuura

Mukai

et al. 2018

Psychiatry Clin Neurosci

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“…Using another conceptual framework, Yanagisawa et al . [39] assessed 256 adults with OCD in Japan and found that in approximately half the cases patients exhibited what the researchers described as “involved behaviors.” These “involved behaviors” included things such as forcing relatives to participate in rituals or to assist in compulsive avoidance. Patients were more likely to be female, have more severe symptoms and respond less well to treatment.…”

Section: Resultsmentioning

confidence: 99%

Family accommodation in obsessive-compulsive and anxiety disorders: a five-year update

Lebowitz

Panza

Bloch

2015

Expert Review of Neurotherapeutics

147

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Family accommodation describes changes that individuals make to their behavior, to help their relative who is dealing with a psychiatric and/or psychological disorder(s), avoid or alleviate distress related to the disorder. Research on family accommodation has advanced rapidly. In this update we aim to provide a synthesis of findings from the past five years. A search of available, peer-reviewed, English language papers was conducted through PubMed and PsycINFO, cross referencing psychiatric disorders with accommodation and other family-related terms. The resulting 121 papers were individually reviewed and evaluated and the main findings were discussed. Family accommodation is common in obsessive-compulsive disorder (OCD) and in anxiety disorders, and manifests similarly across these disorders. Family accommodation is associated with more severe psychopathology and poorer clinical outcomes. Treatments have begun to focus on the reduction of family accommodation as a primary therapeutic goal and finally, neurobiological underpinnings of family accommodation are beginning to be investigated.

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“…Hastalığın aile yaşamına ve sosyal işlevselliğe olumsuz etkileri, hastaların yardım arama davranışını engellemekte, tedaviye uyum ve yanıtı olumsuz etkilemekte ve prognozu kötüleştirmektedir (Gomes ve ark. 2014, Yanagisawa ve ark. 2015.…”

Section: Ailesel Tepkiler Ve Belirtilere Katılımunclassified

Understanding Treatment Response and Resistance in Obsessive Compulsive Disorder in the Context of Cognitive Neuropsyhological Model

Beşiroğlu¹

2016

Turkish Journal of Psychiatry

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ÖZETBilişsel davranışçı terapiler (BDT), antidepresanlar ve nöro-düzenleme teknikleri obsesif kompulsif bozukluğun (OKB) tedavisinde çeşitli aşa-malarda kullanılan güncel tedavi seçenekleridir. Bir psikiyatrik bozuklukta psikolojik yaklaşımlardan cerrahi tekniklere kadar bambaşka yaklaşımları tedavi etkisinde ortak kılan unsurlar ilgili literatürde yeterince tanımlanmamıştır. Bilişsel Nöropsikolojik Model güncel bir yaklaşım olarak farklı psikopatolojiler için psikolojik ve nörobiyolojik modellerin duygusal işlemleme süreçlerinin bozulması aracılığıyla bağdaştığı ortak bir çatı önermektedir. Bu yazıda OKB'de farklı tedavi seçeneklerinin etkinliğini anlamak için yukarıdan-aşağı ve aşağıdan-yukarı bozulmuş duygusal işlemleme süreçlerini bütünleştiren bir yaklaşım tanımlanmış-tır. Bu modele göre bilişsel terapi bilgi işleme yanlılıklarını doğrudan etkilemek yerine, yukarıdan-aşağı duygusal işlemleme süreçleri üzerin-deki etkileri aracılığıyla şemalar üzerinde aşamalı bir kırılma yaratır. Antidepresanlar ve davranışçı terapinin ise beynin duygusal işlemlemesini aşağıdan-yukarı süreçler yoluyla değiştirdiği öne sürülür. OKB'si olan hastalarda BDT ve ilaç tedavisine direnç sık karşılaşılan bir durumdur ve bu tedavi seçeneklerine olumsuz yanıtı yordayan birçok etmen tanımlanmıştır. Belirti şiddeti, bazı özel belirtilerin varlığı, zayıf içgörü, dissosiyasyon eğilimi ve ailesel katılım hem BDT hem ilaç tedavisine direnç ile ilişkili bulunmuş etmenlerdir. Bu farklı etmenlerin varlığını tedavi direnci ile ilişkili kılan altta yatan nedenler Bilişsel Nöropsikolo-jik Model bağlamında tartışılmıştır. In this paper, an integrated approach of disrupted top-down and bottom-up emotional processing has been described to understand the efficacy of the different treatment modalities for OCD. In this model, the cognitive therapy is proposed to contribute to the gradual breakdown of schemata through the effect on top-down emotional processing instead of acting on information processing biases directly. Antidepressant drugs and behavioral therapy are proposed to alter the brain's emotion processing in a bottom-up process. Resistance to pharmacotherapy and CBT is a common problem in the patients with OCD, and a lot of factors have been described as negative predictors of these treatment options. The severity of symptoms, presence of specific symptoms, poorer insight, high level of dissociation and family accommodation are the factors associated with resistance to both pharmacotherapy and CBT. The underlying reasons establishing an association between the presence of these diverse factors and treatment resistance were discussed in the context of CNM.

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Clinically related or predictive factors and impacts on long-term treatment outcomes of involvement behaviors in patients with obsessive–compulsive disorder

Cited by 10 publications

References 32 publications

Ten‐year follow‐up study of Japanese patients with obsessive–compulsive disorder

Ten‐year follow‐up study of Japanese patients with obsessive–compulsive disorder

Family accommodation in obsessive-compulsive and anxiety disorders: a five-year update

Understanding Treatment Response and Resistance in Obsessive Compulsive Disorder in the Context of Cognitive Neuropsyhological Model

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