Clinically impactful metabolic subtypes of pancreatic ductal adenocarcinoma (PDAC)
Jannat Pervin,
Mohammad Asad,
Shaolong Cao
et al.
Abstract:Background: Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease characterized by a diverse tumor microenvironment. The heterogeneous cellular composition of PDAC makes it challenging to study molecular features of tumor cells using extracts from bulk tumor. The metabolic features in tumor cells from clinical samples are poorly understood, and their impact on clinical outcomes are unknown. Our objective was to identify the metabolic features in the tumor compartment that are most clinically impactful.Me… Show more
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