Clinically confirmed congenital rubella syndrome: the role of echocardiography

Mekonnen, Demeke

doi:10.4314/ejhs.v27i2.13

Cited by 12 publications

(4 citation statements)

References 14 publications

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“…Commonly the congenital heart defects in congenital rubella syndrome is atrial septal defect, patent ductus arteriosus, pulmonary artery stenosis, tetralogy of fallot, and ventricular septal defect. 8 In our case it was left-sided obstructive lesions, severe subaortic membrane, patent ductus arteriosus, non-coronary cusp perforation and mild microcephaly. Several studies have documented patent ductus arteriosus (47.5%) as the most common among congenital heart defects followed by atrial septal defect (17.5%) and ventricular septal defect (17%) which is more consistent with this study.…”

Section: Discussionsupporting

confidence: 44%

Case report of congenital rubella syndrome with sub aortic membrane non-coronary cusp perforation and patent ductus arteriosus

et al. 2023

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Rubella, a common viral infection caused primarily by the rubella virus, is still a global public health concern. Every year, about 30000 instances of congenital rubella syndrome are reported in India, according to health ministry surveillance. A case study of a 6-year-old boy with congenital rubella syndrome was presented here. The child presented with classic abnormalities of congenital rubella syndrome like hearing loss, vision problems, heart defects and intellectual disabilities. Among its many manifestations, congenital heart defects are life threatening, this child was planned for surgical correction of above cardiac lesions. Treatment modalities differ in each type of congenital heart defects and its early detection and surgical intervention can reduce childhood mortality and morbidity.

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Section: Discussionsupporting

confidence: 44%

Case report of congenital rubella syndrome with sub aortic membrane non-coronary cusp perforation and patent ductus arteriosus

et al. 2023

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“…Thus, immunization is the best and most effective preventive measure to prevent CRS. 3,[13][14][15][16][17][18] In the study, we aimed to evaluate the diagnostic value of group A and group B clinical manifestations compared to rubella serology results in the diagnosis of CRS at Dr. Zainoel Abidin's Regional General Hospital (ZARGH), Banda Aceh. The results of this study are expected to be the basis for early diagnosis of CRS in children aged 0-12 months, especially in health facilities that lack the facilities to perform serological rubella examinations, such as ZARGH.…”

Section: Resultsmentioning

confidence: 99%

Diagnostic value of clinical manifestations of Group A and Group B compared with rubella serology results in congenital rubella syndrome

Sulasmi,

Dimiati,

Andid

et al. 2024

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Background Congenital rubella syndrome (CRS) is the triad of defects/abnormalities in the heart, eyes, and ears, resulting from rubella virus infection, especially in the first trimester of pregnancy. Manifestations of CRS are divided into Group A including: hearing loss, congenital heart disease, cataracts or glaucoma, and pigmentary; Group consisted of purpura, splenomegaly, microcephaly, mental retardation, retinopathy and icteric radiolucent bone disoreder that appears within 24 hours after birth. CRS diagnosis is based on serologic rubella test results. Comprehensive management of CRS is needed to achieve optimal child development. However, not all referral center hospitals in Indonesia have serological rubella examination modalities. Objective To evaluate the diagnostic value of group A and group B clinical manifestations compared to rubella serology results in the diagnosis of CRS. Methods This cross-sectional study used secondary data from medical records of pediatric patients with suspected CRS who meet the criteria for groups A and B aged less than 12 months who had been hospitalized at Dr. Zainoel Abidin Regional General Hospital, Banda Aceh, during the three-year study period (2019-2021) which have complete data were included in the study. The IgM serology results were used as diagnostic comparison that performed at the age of less than 12 months. Results A total of 126 patients met the inclusion criteria. Sixty-five (51.6%) subjects were male, 80 (63.5%) subjects had normal birth weight, and 89 (70.6%) subjects were aged <6 months. The diagnostic sensitivity for groups A, B, as well as A and B clinical manifestations were 100%, 75%, and 100%, respectively. This excellent sensitivity value suggests that the clinical manifestations of groups A and B would be suitable as screening tools because they could “catch” many patients with suspected CRS. Conclusion The clinical manifestations of group A and group B have excellent diagnostic value as a screening tool for CRS.

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“…Well known environmental causes include excess alcohol consumption during pregnancy resulting in foetal alcohol spectrum disorder [5], as well as Rubella [6] (German measles). Both disrupt normal organ formation and increase the likelihood of atrial or ventricular septal defects.…”

Section: Cardiac Septal Defects Often Coexist With Other Inherited Co...mentioning

confidence: 99%

To What Extent Can Transcatheter Devices Replace Open-Heart Surgery in the Treatment of Cardiac Septal Defects?

Somanathan¹

2022

WJCS

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Transcatheter treatments are widespread, having the advantages of being less invasive than surgery with quicker recovery times and reduced physical and psychological consequences. However correct patient selection is vital to optimise outcomes. In the case of an isolated atrial septal defect (ASD), transcatheter closure is preferred. Whilst multiple or large ASDs or ventricular septal defects (VSDs) are best treated through the transthoracic approach. Furthermore, the development of the transcatheter approach has yielded devices that can be used in the transthoracic approach resulting in hybrid techniques. This article aims to evaluate both transcatheter devices and open-heart surgery in the treatment of cardiac septal defects. A brief discussion follows on from the causes and history of cardiac defect treatments.

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Clinically confirmed congenital rubella syndrome: the role of echocardiography

Cited by 12 publications

References 14 publications

Case report of congenital rubella syndrome with sub aortic membrane non-coronary cusp perforation and patent ductus arteriosus

Case report of congenital rubella syndrome with sub aortic membrane non-coronary cusp perforation and patent ductus arteriosus

Diagnostic value of clinical manifestations of Group A and Group B compared with rubella serology results in congenital rubella syndrome

To What Extent Can Transcatheter Devices Replace Open-Heart Surgery in the Treatment of Cardiac Septal Defects?

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