Clinical versus ultrasound examination in the evaluation of hepatosplenic schistosomiasis mansoni in endemic areas

Imaging techniques and histology in the evaluation of liver fibrosis in hepatosplenic schistosomiasis mansoni in Brazil: a comparative study

“…The sensitivity and specificity of US in the recognition of LF is comparable to histological examination of liver fragments (Cerri et al 1984, Homeida et al 1988a, Abdel-Wahab et al 1989. The development of portable US devices is considered an advance in the investigation of morbidity in field-based studies (Marinho et al 2006). US may also be used to evaluate the dynamic changes produced by portal hypertension and, accordingly, may suggest the presence of oesophageal varices (Abdel-Latif et al 1981, Davidson et al 1991, Abdel-Wahab et al 1993, Richter et al 1998).…”

Serum hyaluronan and collagen IV as non-invasive markers of liver fibrosis in patients from an endemic area for schistosomiasis mansoni: a field-based study in Brazil

“…Considered a simple, safe and low-cost method, after the advent of portable equipment, it has been of invaluable help in the screening of populations living in endemic areas and in field-based studies of the disease. Taken as a nearly ideal tool in the diagnosis and classification of schistosomiasis, it is now used as a surrogate for the gold-standard in the diagnosis of schistosomiasis-related liver fibrosis (Doehring-Schwerdtfeger et al 1989, Abdel-Wahab et al 1992, Richter et al 1992, Abdel-Wahab & Strickland 1993, pinto-Silva et al 1994, Richter 2000, Kariuki et al 2001, Cota et al 2006, Marinho et al 2006, Ruiz-Guevara et al 2007.…”

Clinical and laboratory evaluation of schistosomiasis mansoni patients in Brazilian endemic areas

“…The percentage of patients with anaemia and low platelet counts was slightly altered. This may have been caused by the existence of a hepatosplenic form that was not detected in the physical examination by means of liver and spleen exams, which confirms the importance of abdominal ultrasound as a complementary examination to evaluate the presence of hepatosplenomegaly (Marinho et al 2006).…”