Clinical validation of the Deltatrac monitoring system in mechanically ventilated patients

Tissot, S.; Delafosse, B.; Bertrand, Olivier; Bouffard, Y.; Viale, J. P.; Annat, G.

doi:10.1007/bf01726538

Cited by 107 publications

(63 citation statements)

References 11 publications

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“…This technique has been described as the gold standard in indirect calorimetry and has been validated in the measurement of RMR in both adults and children (Weissman et al 1990;Tissot et al 1995). After a 30 min seated resting period, participants were instructed to lie in a comfortable supine position.…”

Section: Preliminary Testingmentioning

confidence: 99%

The impact of high-intensity intermittent exercise on resting metabolic rate in healthy males

et al. 2013

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High intensity intermittent exercise training (HIT) may favourably alter body composition despite low training volumes and predicted energy expenditure (EE). Purpose: to characterise the acute impact of two common HIT protocols on EE and post-exercise oxygen consumption (11 h EPOC). Methods: oxygen consumption (l·min -1 ), respiratory exchange ratio (RER) and EE were measured in nine healthy, lean males over 12 h under three conditions: control (CON), HIT1 (10x one min high intensity cycling bouts followed by one min rest) and HIT2 (10x four min high intensity cycling bouts followed by two min rest). Results: total exercise period EE during HIT1 (1151 ± 205 kJ) (mean ± SD) was significantly lower than HIT2 (2788 ± 322 kJ; p < 0.001). EE within the 60 min after exercise was significantly albeit marginally higher after HIT1 (388 ± 44 kJ; p = 0.02) and HIT2

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Section: Preliminary Testingmentioning

confidence: 99%

The impact of high-intensity intermittent exercise on resting metabolic rate in healthy males

et al. 2013

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“…Metabolic carts, such as the Deltatrac, have been shown to be reliable instruments for measuring RMR (Takala et al, 1989;Weissman et al, 1990;Tissot et al, 1995). Despite the advantages of the Deltatrac, there are factors that deter its use (Nieman et al, 2003;St-Onge et al, 2003).…”

Section: Introductionmentioning

confidence: 99%

Comparison between Medgem and Deltatrac resting metabolic rate measurements

et al. 2005

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Objective: The primary aims of this trial were to evaluate the reproducibility of a portable handheld calorimeter (Medgem) in a clinical population, and to compare its measures with a calorimeter in typical use with these patients. Design: Cross-sectional clinical validation study. Setting: Outpatient Clinical Research Center. Subjects: A total of 24 stable home nutrition support patients. Interventions: In random order three measures of resting metabolic rate (RMR) were taken after a 4-h fast, 15 min rest and 2-h abstention from exercise. Two measures were taken with the same Medgem (MG) and one with the traditional calorimeter (Deltatrac). Reproducibility of MG measures and their comparability to a Deltatrac measure were assessed by Bland-Altman analysis, with 47250 kcal/day established a priori as a clinically unacceptable error. In addition, disagreement between the two types of measures was defined as greater than 10% difference. Results: The mean difference between two MG measures was À6.8 kcal/day, with limits of agreement between 233 and À247 kcal/day and clinically acceptable. The mean difference between the Deltatrac and mean of two MG measures was À162 kcal/day, with limits of agreement between 577 and À253 kcal/day and clinically unacceptable. In all, 80% of the repeated MG RMR measures agreed within 10%, and the mean MG reading agreed with the Deltatrac in 60% of cases. Conclusions: RMR obtained using the MG calorimeter has an acceptable degree of reproducibility, and is acceptable to patients. The MG measures, however, are frequently lower than traditional measures and require further validation prior to application to practice in this vulnerable patient group.

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“…Validation and calibration of this device has previously been described. [9][10][11][12] The measurement error of the indirect calorimeter for whole-body VO 2 is Ϯ2% to 4% at an FIO 2 of 0.4. 10,12 Thus, observed VO 2 increases or decreases of more than 4% were considered not attributable to measurement error.…”

Section: Methodsmentioning

confidence: 99%

Is there occult tissue ischemia in chronic end-stage liver disease?

et al. 1999

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Whether pathological oxygen supply dependency exists in patients with chronic end-stage liver disease (CESLD) is unknown, although the frequently occurring multiorgan dysfunction seen in these patients may be the result of occult tissue ischemia. In this study, 15 adult patients with CESLD were evaluated for the presence of pathological oxygen supply dependency and, thus, occult tissue ischemia before undergoing orthotopic liver transplantation. Whole-body oxygen consumption (VO 2 ) was measured using indirect calorimetry at baseline, at reduced oxygen delivery (DO 2 ) using positive end-expiratory pressure, and at increased DO 2 using volume infusion. As a group, no significant increase or decrease in VO 2 was observed with changes in DO 2 . However, 4 patients showed increases in VO 2 of 14%, 10.8%, 9.6%, and 8.2% when DO 2 was increased. The study results suggest that pathological oxygen supply dependency is present in a subset of patients with CESLD, and the existence of occult tissue ischemia is speculated. Copyright 1999 by the American Association for the Study of Liver DiseasesU nder normal conditions, whole-body oxygen consumption (VO 2 ) is independent of oxygen delivery (DO 2 ) over a wide range of DO 2 values. As DO 2 decreases from normal levels, oxygen extraction from hemoglobin (Hgb) increases, preserving VO 2 . However, if DO 2 decreases to less than a critical level, VO 2 begins to decrease as oxygen extraction reaches its physiological maximum. This is termed physiological oxygen supply dependency. It has been suggested that in certain disease states, such as adult respiratory distress syndrome (ARDS), 1-4 sepsis, 5-7 and fulminant hepatic failure (FHF), 8 pathological oxygen supply dependency may exist. In this condition, also known as pathological DO 2 dependency, increases in DO 2 to greater than normal or even supranormal levels result in progressive increases in VO 2 , with relative preservation of oxygen extraction. Explanations for this seemingly inappropriate DO 2 dependency remain speculative, but ongoing occult tissue ischemia cannot be conclusively excluded. Although a number of studies have been performed suggesting the presence of pathological DO 2 dependency, inherent methodological flaws, most frequently the use of mathematically coupled calculations for both DO 2 and VO 2 , have favored the false demonstration of pathological DO 2 dependency and thus render these studies inconclusive.Whether patients with chronic end-stage liver disease (CESLD) have pathological DO 2 dependency is unknown. This patient population is unique in that the presence of a hyperdynamic circulation coupled with a high mixed-venous oxygen content is suggestive of luxury capillary perfusion. It can be postulated that the hyperdynamic circulation seen in CESLD is an adaptive response to occult tissue ischemia caused by profound arteriovenous shunting with resultant inadequate organ perfusion. Thus, it is possible that the frequently occurring multiorgan dysfunction seen in CESLD is the result of occult tiss...

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Clinical validation of the Deltatrac monitoring system in mechanically ventilated patients

Cited by 107 publications

References 11 publications

The impact of high-intensity intermittent exercise on resting metabolic rate in healthy males

The impact of high-intensity intermittent exercise on resting metabolic rate in healthy males

Comparison between Medgem and Deltatrac resting metabolic rate measurements

Is there occult tissue ischemia in chronic end-stage liver disease?

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