Clinical Utility of the QuantiFERON TB-2G Test for Elderly Patients With Active Tuberculosis

Kobashi, Yoshihiro; Mouri, Keiji; Yagi, Shinich; Obase, Yasushi; Miyashita, Naoyuki; Okimoto, Niro; Matsushima, Toshiharu; Kageoka, Takeshi; Oka, M.

doi:10.1378/chest.07-1995

Cited by 99 publications

(85 citation statements)

References 15 publications

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“…The Swiss study [36] suggested higher sensitivity of T-SPOT.TB and QFT-G In-Tube than TST in detecting LTBI, with moderate agreement of the two IGRAs and confirmation of their unreliability in detecting prior TB. The Japanese study [37] confirmed better results of QFT-G In-Tube over TST in detecting LTBI.…”

Section: Chronic Patients Undergoing Haemodialysismentioning

confidence: 94%

Steps forward in LRTI and tuberculosis: update from the ERS Respiratory Infections Assembly

Blasi

Cosentini

Migliori

et al. 2009

European Respiratory Journal

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Lower respiratory tract infections (LRTIs) and tuberculosis are among the leading reasons for seeking medical care.In the present report, the most recent advances in the fields of clinical research and basic science of LRTIs and tuberculosis are presented through analysis of some of the best abstracts presented at the 18th European Respiratory Society Annual Congress in Berlin.The role of viruses in chronic obstructive pulmonary disease exacerbations and the importance of new biomarkers in the diagnosis of bacterial infections in LRTI are discussed.New tools for the diagnosis of latent and active tuberculosis in special subgroups of patients (children, immunocompromised individuals, etc.), and the new epidemiological threat of multidrug-resistant and extensively drug-resistant tuberculosis cases is analysed.

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Section: Chronic Patients Undergoing Haemodialysismentioning

confidence: 94%

Steps forward in LRTI and tuberculosis: update from the ERS Respiratory Infections Assembly

Blasi

Cosentini

Migliori

et al. 2009

European Respiratory Journal

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“…69 As regards aged patients, the data available show that QFT-G is more sensitive than TST in patients older than 80 years with active TB. 70,71 Although the sensitivity of QFT-G decreased with age, it remained better than that of TST.…”

Section: Interferon-γ-based Assays For Diagnosing Active Tuberculosismentioning

confidence: 99%

Diagnosis of tuberculosis infection using interferon-γ-based assays

Cerezales

Benítez

2011

Enfermedades Infecciosas y Microbiología Clínica

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“…The type of treatment administered has also been considered to be an important factor affecting patient outcome (26 (27) reported the usefulness of (27)(28)(29)(30). In such situations, the decrease of production IFN-γ from lymphocytes is associated with an indeterminate or negative result of QFT-2G (25).…”

Section: T a B L E 5 De T A I L S O F 1 0 Ca S E S E X A Mi N E D Bmentioning

confidence: 99%

Active Tuberculosis in Patients Undergoing Hemodialysis for End-stage Renal Disease: A 9-year Retrospective Analysis in a Single Center

et al. 2009

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Objective Tuberculosis (TB) (HR 8.86, p=0.04), and underweight (HR 10.88, p=0.02). The sensitivity of and polymerase chain reaction was 50, 80, and 88.2% years from the initiation of dialysis. Most patients presented with fever (84.2%) and extrapulmonary TB (57.9%). The mortality rate within 24 weeks of the initiation of TB treatment was 36.8%. The factors associated with mortality were: a short duration of dialysis

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Clinical Utility of the QuantiFERON TB-2G Test for Elderly Patients With Active Tuberculosis

Cited by 99 publications

References 15 publications

Steps forward in LRTI and tuberculosis: update from the ERS Respiratory Infections Assembly

Steps forward in LRTI and tuberculosis: update from the ERS Respiratory Infections Assembly

Diagnosis of tuberculosis infection using interferon-γ-based assays

Active Tuberculosis in Patients Undergoing Hemodialysis for End-stage Renal Disease: A 9-year Retrospective Analysis in a Single Center

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