Clinical uses of the female sex hormones and early diagnosis and treatment of mammary cancer

Hart, P.G.

doi:10.1016/0028-2243(73)90080-4

European Journal of Obstetrics & Gynecology and Reproductiv

1973

DOI: 10.1016/0028-2243(73)90080-4

|View full text |Cite

Clinical uses of the female sex hormones and early diagnosis and treatment of mammary cancer

P.G. Hart¹

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

1984

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Androgen Receptors and Antiandrogen Therapy for Laryngeal Carcinoma

Mattox¹,

Hoff²,

McGuire³

1984

Archives of Otolaryngology - Head and Neck Surgery

View full text Add to dashboard Cite

\s=b\A hydroxylapatite assay was used to assay androgen receptor levels in 23 primary laryngeal carcinomas, nine metastatic laryngeal carcinomas, and three oropharyngeal carcinomas. The median androgen receptor level in laryngeal carcinoma was 0.7 femtomoles of receptor protein per milligran of cytosol protein. Ten patients with advanced or metastatic laryngeal carcinoma and one patient with metastatic floor of mouth carcinoma were treated with the antiandrogen flutamide. There were three short-lived partial responses (1, 2, and 2.5 months) in nine patients whose tumors could be evaluated for response. Toxic reactions consisted of mild breast tenderness, and hypercalcemia in two patients with bone metastases. Androgen receptor levels did not correlate with response to flutamide.The low androgen receptor levels in laryngeal tumors may account for the relative inactivity of the antiandrogen in laryngeal cancer.

show abstract

Androgen Receptors and Antiandrogen Therapy for Laryngeal Carcinoma

Mattox¹,

Hoff²,

McGuire³

1984

Archives of Otolaryngology - Head and Neck Surgery

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

hi@scite.ai

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Clinical uses of the female sex hormones and early diagnosis and treatment of mammary cancer

Cited by 1 publication

References 0 publications

Androgen Receptors and Antiandrogen Therapy for Laryngeal Carcinoma

Androgen Receptors and Antiandrogen Therapy for Laryngeal Carcinoma

Contact Info

Product

Resources

About