Clinical, ultrasonographic and optical coherence tomography correlation of optic nerve head cupping in glaucoma patients

Pujari, Amar; Swamy, Deepa R; Selvan, Harathy; Agarwal, Divya; Sihota, Ramanjit; Gupta, Sikha; Gupta, Nikita; Dada, Tanuj

doi:10.4103/ijo.ijo_24_19

Cited by 4 publications

(3 citation statements)

References 16 publications

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“…Ultrasonography has been described in literature as a reliable surrogate tool that can be used in quantifying Optic nerve head (ONH) cupping in cases of media opacities which preclude optic disk visualization, although this cannot be considered as the best tool for disk evaluation. [ 9 10 11 ]…”

Section: Methodsmentioning

confidence: 99%

Incidence and risk factors for post-penetrating keratoplasty glaucoma

Shree

Gandhi²,

Dave³

et al. 2022

Indian Journal of Ophthalmology

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Purpose: To carry out a prospective study to analyze the incidence and various preoperative, intraoperative, and postoperative risk factors for the development of PPKG. Methods: A total of 207 patients were analyzed prospectively, who were operated for penetrating keratoplasty (PK) in a tertiary eye care hospital between the time period of August 1, 2017 and February 28, 2018 and were followed up till the sixth month. Each patient was analyzed at every visit to determine the factors responsible for post-keratoplasty glaucoma. Results: Out of 207 eyes, post-PK glaucoma developed in 84 cases, which yielded an incidence of 41%. Incidence of PPKG (Post PK glaucoma) in various conditions was as follows: in repeat PK 62%, in perforated corneal ulcer 33%, in nonperforated corneal ulcer 29%, in corneal scar including adherent leukoma 37.2%, and in pseudophakic bullous keratopathy and aphakic bullous keratopathy, 14% and 80%, respectively. In age- and sex-adjusted multivariate analysis, the significant risk factors were age ( P -value- 0.006), presence of PAS ( P -value 0.001), and fellow eye glaucoma ( P -value 0.04). Aphakia and combined surgery were not found to be significant Conclusion: Our study recommends a meticulous examination of the fellow eye to assess the presence of glaucoma as it can increase the suspicion of glaucoma in the eye to be operated. The presence of PAS and age are important risk factors for developing PPKG. The risk of developing PPKG increases exponentially as the number of risk factors increases, but the presence of more than three risk factors does not add to the development of PPKG.

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Section: Methodsmentioning

confidence: 99%

Incidence and risk factors for post-penetrating keratoplasty glaucoma

Shree

Gandhi²,

Dave³

et al. 2022

Indian Journal of Ophthalmology

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“…Ultrasound B scan of RE was anechoic and confirmed glaucomatous optic nerve head cupping. 4 Anterior segment optical coherence tomography (Figure 1(b)) and ultrasound biomicroscopy (online Supplemental Video) confirmed a slit-like defect communicating with the anterior chamber and clear contents. An etiological diagnosis of RE post-traumatic complicated pseudophakia with secondary angle closure glaucoma leading to wound gape and a communicating sub-tenon cyst was made.…”

Section: Case Reportmentioning

confidence: 92%

The high-pressure bleb

Selvan

Lakra

Yadav

et al. 2021

European Journal of Ophthalmology

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A 45-year-old male presented with a slowly progressive, painless swelling in his right eye for the past 6 months. He had undergone an open globe injury repair 10 years back and an eventful cataract surgery 5 years back. The presenting visual acuity in the affected eye was perception of light with inaccurate projection of rays. The intraocular pressure was 44 mm Hg with advanced glaucomatous cupping. The swelling was identified to be a communicating sub-tenon cyst secondary to scleral wound dehiscence from secondary angle closure glaucoma. Wound re-suturing, cyst excision and diode laser cyclophotocoagulation was performed in a single sitting, with explained poor visual prognosis.

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“…The left eye fundus fluorescein angiography was normal. Ocular ultrasound B-scan of the right eye showed a deep cupping 3 with thinner optic nerve and suspected meningeal thickening but without any obvious retrobulbar masses in either eye. Computed tomography scan of head and orbit confirmed a thinned out right optic nerve sheath complex.…”

Section: Case Reportmentioning

confidence: 97%

Case Report: Pediatric Ocular Ischemia and Neovascular Glaucoma in Neurofibromatosis Type 1

Selvan¹,

Surve

Sharma

et al. 2022

Optom Vis Sci

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SIGNIFICANCENeovascular glaucoma is an important subset of secondary glaucoma in neurofibromatosis patients. Vasculopathy of the ophthalmic circulation needs to be borne in mind while evaluating their etiology.PURPOSEThis study aimed to report the presentation, diagnostic work-up and management of an unusual case of neovascular glaucoma in a child.CASE REPORTA 7-year-old boy presented with uniocular ischemic fundus and secondary neovascular glaucoma. Detailed family history and evaluation led to a diagnosis of familial neurofibromatosis type 1. Fundus fluorescein angiography revealed compromised retinal and choroidal circulations in the affected eye. Ocular ultrasound B scan and neuroimaging did not show any contributory lesions. Cardiovascular evaluation was within normal limits. Ophthalmic Doppler imaging revealed normal proximal ophthalmic arteries in both eyes; however, the central retinal artery of the affected eye showed low flow in its proximal part and absent flow in the distal part, as compared with the fellow eye showing regular flow until the optic disc margin. Corroborating the clinical, fundus fluorescein angiography and Doppler findings, a diagnosis of neurofibromatosis type 1–related vasculopathy of the distal ophthalmic artery was made. Poor visual prognosis for the affected eye was explained, and anterior retinal cryopexy along with cyclocryotherapy was performed to treat the neovascular glaucoma.CONCLUSIONSVasculopathy of the ophthalmic circulation is an important cause of neovascular glaucoma in neurofibromatosis patients. The morphology of Lisch nodules may be altered in an ischemic eye, and therefore, careful examination of the other eye and systemic evaluation is vital in such unusual scenarios.

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Clinical, ultrasonographic and optical coherence tomography correlation of optic nerve head cupping in glaucoma patients

Cited by 4 publications

References 16 publications

Incidence and risk factors for post-penetrating keratoplasty glaucoma

Incidence and risk factors for post-penetrating keratoplasty glaucoma

The high-pressure bleb

Case Report: Pediatric Ocular Ischemia and Neovascular Glaucoma in Neurofibromatosis Type 1

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