Clinical trials in-a-dish for cardiovascular medicine
Xuekun Wu,
Kyle Swanson,
Zehra Yildirim
et al.
Abstract:Cardiovascular diseases persist as a global health challenge that requires methodological innovation for effective drug development. Conventional pipelines relying on animal models suffer from high failure rates due to significant interspecies variation between humans and animal models. In response, the recently enacted Food and Drug Administration Modernization Act 2.0 encourages alternative approaches including induced pluripotent stem cells (iPSCs). Human iPSCs provide a patient-specific, precise, and scree… Show more
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