Clinical trial with subdermal implants of the progestin R-2323

Dı́az, Soledad; Pavéz, Margarita; Quinteros, Eliana; Robertson, Donald S.; Croxatto, Horacio B.

doi:10.1016/0010-7824(77)90083-x

Search citation statements

Order By: Relevance

Paper Sections

Select...

Introduction2

Citation Types

Supporting

Mentioning

Contrasting

Year Published

1978

1991

Publication Types

Select...

Article5

Relationship

Self Cite0

Independent5

Authors

Journals

Cited by 13 publications

(2 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Progestogen only preparations were observed to cause less impairment of glucose tolerance as compared to estrogen-progestogen combination preparations [6,7].…”

Section: Introductionmentioning

confidence: 89%

See 1 more Smart Citation

Short-term and long-term effects of NorplantR-2 on plasma lipoproteins and glucose tolerance

1991

View full text Add to dashboard Cite

Twenty-five women using the levonorgestrel-containing contraceptive implant, Norplant-2, were studied longitudinally, to see the effects on lipid profile, glucose tolerance and hepatic transaminases with short-term (12 weeks) and long-term (18 to 24 months) use of Norplant-2 [corrected]. Total lipids, cholesterol, phospholipids, triglycerides and their subfractions were evaluated. There was a significant increase in LDL-cholesterol after 12 weeks of use (p less than 0.05), which did not persist at 18-24 months follow-up. The HDL-cholesterol, HDL/LDL-cholesterol ratio, phospholipids, other lipid fractions, hepatic transaminases and glucose tolerance did not alter significantly following short-term or long-term use of Norplant-2.

show abstract

“…Progestogen only preparations were observed to cause less impairment of glucose tolerance as compared to estrogen-progestogen combination preparations [6,7].…”

Section: Introductionmentioning

confidence: 89%

“…With subdermal implants of R-2323, altered liver function tests were observed [6], but not with implants of other progestogens, including Norplant R (six capsules) [7,8].…”

Section: Introductionmentioning

confidence: 96%