Clinical trial of esmolol‐induced controlled hypotension with or without acute normovolemic hemodilution in spinal surgery*

Lim, Young-Jin; Kim, C. S.; Bahk, Jae Hyon; Ham, Byung-Moon; H., S.

doi:10.1034/j.1399-6576.2003.470113.x

Cited by 31 publications

(19 citation statements)

References 18 publications

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“…However, based on their known pharmacological effects, beta blockers decrease CO and therefore decrease the flow to the tissue. However, beta blockade would only be appropriate for capillary bleeding [15].…”

Section: Discussionmentioning

confidence: 99%

Effects of preoperative oral beta blocker versus intraoperative nitroprusside or esmolol on quality of surgical field during tympanoplasty

Amr

Amin

2011

Journal of Clinical Anesthesia

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Section: Discussionmentioning

confidence: 99%

Effects of preoperative oral beta blocker versus intraoperative nitroprusside or esmolol on quality of surgical field during tympanoplasty

Amr

Amin

2011

Journal of Clinical Anesthesia

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“…39 A randomized controlled trial by Lim et al found that ANH coupled with intraoperative esmolol-induced hypotension in spine surgery significantly reduced the incidence of allogenic blood transfusion (67% vs. 100%). 40 However, the evidence regarding ICS was conflicting. A randomized controlled trial by Zhang et al showed that ICS significantly reduced the incidence of allogenic blood transfusion in patients undergoing scoliosis surgery (31% vs. 100%).…”

Section: Discussionmentioning

confidence: 99%

Effect of intraoperative autologous transfusion techniques on perioperative hemoglobin level in idiopathic scoliosis patients undergoing posterior spinal fusion: A prospective randomized trial

Hasan

Choe

Chan

et al. 2017

J Orthop Surg (Hong Kong)

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Background: Massive blood loss during posterior spinal fusion for adolescent idiopathic scoliosis remains a significant risk for patients. There is no consensus on the benefit of acute normovolemic hemodilution (ANH) or intraoperative cell salvage (ICS) in scoliosis surgery. Methods: Patients were randomized to one of two groups. Group A received ANH and ICS during operation, while group B received only ICS. Patients' age, sex, height, weight, body blood volume, number of fusion level, Cobb angle, number of screws, duration of surgery, and skin incision length were recorded. Hemoglobin and hematocrit levels were obtained preoperatively and postoperatively (0 h and 24 h). Results: There were 22 patients in each group. There was no significant difference in total blood loss. The perioperative decrease in hemoglobin levels between preoperation and postoperation 24 h (group A 2.79 + 1.15 and group B 2.76 + 1.00) showed no significant difference (p ¼ 0.93). Group A observed a larger decrease in hemoglobin levels at postoperative 0 h relative to preoperative level (2.57 + 0.82 g/dl), followed by a smaller decrease within the next 24 h (0.22 + 1.33 g/dl). Group B showed a continued drop in hemoglobin levels of similar magnitude at postoperation 0 h (1.60 + 0.67 g/dl) and within the next 24 h (1.16 + 0.78 g/dl). One patient from group B received 1 unit of allogenic blood transfusion (p ¼ 0.33). Conclusions: The addition of ANH to ICS in posterior spinal fusion surgery for AIS resulted in a similar decrease in hemoglobin levels between preoperative values and at 24 h postoperatively.

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“…Beta blockers decrease CO and therefore decrease the blood flow to the tissue. So, beta blocker would be appropriate for decreasing the bleeding which result from capillary injury [31][32][33][34][35].…”

Section: Discussionmentioning

confidence: 99%

Controlled Hypotensive Anesthesia in Children Undergoing Nasal Surgery

Amin¹,

Elmawy²

2016

J Anesth Clin Res

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Background: The nasal surgery in pediatric patient's caries a major challenge to both anesthesiologist and surgeon. The surgeon faces small nostrils and narrow nasal passages. The anesthesiologist has to produce condition which facilitate the surgery, decrease the operative time by minimize the intraoperative bleeding to allow better visualization this can be achieved by controlled hypotensive anesthesia which is the key issue in the success of nasal surgery in pediatric age group.

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Clinical trial of esmolol‐induced controlled hypotension with or without acute normovolemic hemodilution in spinal surgery*

Abstract: Our data suggest that ANH of moderate degree can be combined with esmolol-induced CH to improve blood conservation in surgical patients.

Cited by 31 publications

References 18 publications

Effects of preoperative oral beta blocker versus intraoperative nitroprusside or esmolol on quality of surgical field during tympanoplasty

Effects of preoperative oral beta blocker versus intraoperative nitroprusside or esmolol on quality of surgical field during tympanoplasty

Effect of intraoperative autologous transfusion techniques on perioperative hemoglobin level in idiopathic scoliosis patients undergoing posterior spinal fusion: A prospective randomized trial

Controlled Hypotensive Anesthesia in Children Undergoing Nasal Surgery

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