Clinical Syndromes of the Thalamic Stroke In the Classical Vascular Territories: A Prospective Hospital-Based Cohort Study

Abstract

The aim: We aimed to determine, describe, and analyze the clinical and neuroimaging features of vascular syndromes of acute thalamic stroke in the classical vascular territories in a prospective hospital-based cohort study. Materials and methods: We have prospectively recruited 319 acute stroke patients, admitted to the Neurological Center at an academic hospital (Oleksandrivska Clinical Hospital) in Kyiv, Ukraine. Complex neurological, clinical, laboratory, ultrasound, and neuroimaging examinations were performed to all study patients within 24 hours since the symptoms onset. Results: MRI/CT-proven thalamic stroke was diagnosed in 34 (10.6%) out of 319 patients, forming a study group. Twenty-two out of 34 patients (average age 61.9 ± 10.2 years) were diagnosed with an acute isolated ischemic thalamic stroke, and 12 patients (average age 59.0 ± 9.6 years) were diagnosed with an acute thalamic hemorrhage. Conclusions: Specific neurological features of clinical vascular syndromes of acute thalamic stroke in the classical vascular territories were analyzed, compared, and described.

Depression and anxiety in acute ischemic stroke involving the anterior but not paramedian or inferolateral thalamus

“…Contrary to our results, in a small cohort of 9 patients with acute inferolateral thalamic stroke, which however spread to the internal capsule in most patients, ⁓45% showed symptoms of longing, apathy, and fear. Patients with anterior thalamic stroke were not included in this earlier study ( Prokopiv and Fartushna, 2020 ). Based on our and previous studies together with anatomical evidence, it can be concluded that the anterior thalamic nuclei play a role in emotion processing, most likely by connecting the anterior thalamus to the limbic system via the cingulate cortex and entorhinal cortex, the so-called medial limbic loop ( Schmahmann, 2003 ; Chen et al, 2016 ).…”

“…In a retrospective cohort study, patients with chronic inferolateral thalamic stroke revealed increased anxiety and reduced quality of life comprising mental and physical health ( Liebermann et al, 2013 ), however with very heterogeneous timing of examinations (37.2 ± 28.4 months post-stroke). In a small cohort of 9 patients with acute inferolateral thalamic stroke, which however spread to the internal capsule in most patients, ⁓45% showed symptoms of longing, apathy, and fear ( Prokopiv and Fartushna, 2020 ).…”

Особливості Нелакунарного Інсульту Варолієвого Моста: Результати Госпітального Проспективного Когортного Дослідження І Презентація Серії Клінічних Випадків У Білих Дорослих Європейців

“…The work is a part of the posterior circulation stroke study. Its settings, parents, definitions, inclusion, and exclusion criteria have been reported in detail previously [12][13][14][15][16][17][18][19][20][21].…”

Особливості Лакунарного Інсульту Варолієвого Моста: Результати Госпітального Проспективного Когортного Дослідження

“…The study settings, patterns, definitions, inclusion, and exclusion criteria have been reported in detail previously [16][17][18][19][20][21][22][23][24]. Briefly, 120 patients with MRI-positive acute posterior circulation stroke were consecutively selected.…”