Clinical Study on Treatment of Diarrhea Irritable Bowel Syndrome with Wumei Pill Combined with Pividebromide Tablets

Zhao, Shilin; Wang, Yao; Lv, Bolin; Feng, Wenzhe

doi:10.26855/ijcemr.2021.04.004

Cited by 2 publications

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“…Irritable bowel syndrome (IBS) is a common functional gastrointestinal disease characterized by abdominal pain and discomfort and changes in intestinal function [ 1 ]. According to Rome IV, the diagnostic criteria of IBS are defined as follows: (1) Recurrent abdominal pain occurred at least 6 months before the diagnosis of IBS, and abdominal pain occurred at least one day a week for the last 3 months, accompanied by two or more of the following abnormal changes: (1) related to defecation, (2) accompanied by changes in defecation frequency, and (3) accompanied by changes in fecal traits (appearance).…”

Section: Introductionmentioning

confidence: 99%

Effect of Shugan Jianpi Recipe Combined with Cross Moxibustion on Biochemical Examination Indexes and Total Score of TCM Symptoms in Patients with Spleen-Stomach Damp-Heat Diarrhea Irritable Bowel Syndrome

Liu

Ruan²,

Tong³

et al. 2022

Computational and Mathematical Methods in Medicine

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Objective. To explore the effect of Shugan Jianpi recipe combined with cross moxibustion on biochemical examination indexes and total score of TCM symptoms in patients with spleen-stomach damp-heat diarrhea irritable bowel syndrome (IBS). Methods. Sixty patients with spleen-stomach damp-heat diarrhea (IBS) treated in our hospital from January 2019 to September 2021 were enrolled. The patients were randomly assigned into the control group and study group. The control group was treated with Chang Shugan Jianpi recipe, and the study group was treated with Shugan Jianpi recipe combined with cross moxibustion. The curative effect, single symptom score, total score of TCM clinical symptoms, plasma gastrointestinal hormone level, IBS-QOL score, and recurrence were compared. Results. First of all, we compared the curative effects. The study group was significantly effective in 24 cases, effective in 5 cases, and ineffective in 1 case, and the effective rate was 96.67%. In the control group, 13 cases were markedly effective, 10 cases were effective, and 7 cases were ineffective, and the effective rate was 76.67%. The effective rate of the study group was higher compared to the control group ( P < 0.05 ). Secondly, the individual symptom scores were compared. Compared between the two groups, the scores of diarrhea times, stool characteristics, abdominal pain, and abdominal distension in the study group were lower compared to the control group ( P < 0.05 ). After treatment, the total score of TCM clinical symptoms decreased. Compared between the two groups, the total score of TCM clinical symptoms in the study group was lower compared to the control group at 1 week, 2 weeks, and 4 weeks after treatment ( P < 0.05 ). After treatment, the levels of 5-HT and VIP decreased. The levels of 5-HT and VIP in the study group were lower compared to the control group ( P < 0.05 ). The scores of anxieties, health worry, behavioral disorder, social reaction, somatic intention, interpersonal relationship, dietary concern, and sexual behavior in the study group were lower compared to the control group. The IBS-QOL scores were significantly lower compared to the control group ( P < 0.05 ). Finally, we compared the recurrence. The recurrence rate in the study group was lower compared to the control group ( P < 0.05 ). Conclusion. The prescription combined with cross moxibustion has the effect of soothing the liver and invigorating the spleen, resolving dampness and stomach, and can reduce the main clinical symptoms of patients with diarrhea IBS of spleen-stomach damp-heat type, and the overall effect is significant. It can also enhance the emotional state of anxiety and depression and achieve the overall psychological and physical balance and health state, and the recurrence rate is low, which can be further applied in clinic.

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Section: Introductionmentioning

confidence: 99%

Effect of Shugan Jianpi Recipe Combined with Cross Moxibustion on Biochemical Examination Indexes and Total Score of TCM Symptoms in Patients with Spleen-Stomach Damp-Heat Diarrhea Irritable Bowel Syndrome

Liu

Ruan²,

Tong³

et al. 2022

Computational and Mathematical Methods in Medicine

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Case Report of Chronic Diarrhea Treated with <italic>Omae-hwan</italic>

Ahn¹,

Kim²,

Yoon³

et al. 2023

J Int Korean Med

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Objectives: This study reported a clinical case of a chronic diarrhea patient who showed improvement with Korean medicine treatment.Methods: A patient with chronic diarrhea was treated with herbal medicine (Omae-hwan and Omae-hwan-ryo), acupuncture, cupping, and moxibustion. Changes in stool form were measured using the Bristol Stool Scale (BSS). The frequency of defecation was checked every day. The Short Form 36-Item (SF-36) was used to compare patients’ quality of life before and after treatment.Results: Korean medicine treatment improved the stool form, frequency of defecation, and quality of life.Conclusion: Korean medicine treatment containing Omae-hwan and Omae-hwan-ryo improves clinical symptoms and quality of life.

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Clinical Study on Treatment of Diarrhea Irritable Bowel Syndrome with Wumei Pill Combined with Pividebromide Tablets

Cited by 2 publications

References 1 publication

Effect of Shugan Jianpi Recipe Combined with Cross Moxibustion on Biochemical Examination Indexes and Total Score of TCM Symptoms in Patients with Spleen-Stomach Damp-Heat Diarrhea Irritable Bowel Syndrome

Effect of Shugan Jianpi Recipe Combined with Cross Moxibustion on Biochemical Examination Indexes and Total Score of TCM Symptoms in Patients with Spleen-Stomach Damp-Heat Diarrhea Irritable Bowel Syndrome

Case Report of Chronic Diarrhea Treated with <italic>Omae-hwan</italic>

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