Clinical study on the role of platelet-rich plasma in human acellular dermal matrix with razor autologous skin graft repair of giant congenital pigmented nevus in children

Jin, Fei; Li, Xiang; Chen, Jigang; Liu, Jing; Wang, Yining

doi:10.1016/j.bjps.2024.01.056

Cited by 2 publications

(1 citation statement)

References 28 publications

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“…Human acellular dermal matrix (HADM) transplantation can treat giant congenital melanocytic nevi (GCMN) in children, and its combination with PRP treatment can improve the survival rate of transplant vessels. 8 In addition, during the process of skin transplantation, the donor site often experiences delayed healing and segmental pain and itching at the donor site. Using PRP or PRGF at the donor site can effectively reduce postoperative pain and accelerate healing in the donor area.…”

Section: Methodsmentioning

confidence: 99%

The Application of Blood Products in Plastic Surgery: A Systematic Review

Zhuang,

Chen,

Zheng

et al. 2024

Plastic and Reconstructive Surgery - Global Open

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Background: Due to their minimal trauma and relative safety, blood products are becoming increasingly popular in medical aesthetics. In recent years, research on the application of blood products has also been increased. This article will summarize the research progress of emerging blood products in plastic surgery in recent years. Methods: We searched the PubMed database for literature related to the application of blood preparation in plastic surgery over the past 5 years and summarized them. Results: Commonly used in plastic surgery are platelet-rich plasma, platelet-rich fibrin, concentrated growth factor, platelet-poor plasma, and mesenchymal stem cells derived from blood products. They can be used for wound repair and skin and autologous fat transplantation, and can be combined with laser therapy and facial rejuvenation. Conclusions: Understanding the application pathways of blood products in plastic surgery and their respective advantages and disadvantages can help us better choose and use them.

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Section: Methodsmentioning

confidence: 99%

The Application of Blood Products in Plastic Surgery: A Systematic Review

Zhuang,

Chen,

Zheng

et al. 2024

Plastic and Reconstructive Surgery - Global Open

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Platelet-Rich Plasma in Pediatric Surgery: A Comprehensive Review

Di Mitri,

D’Antonio,

Collautti

et al. 2024

Children

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Platelet-Rich Plasma (PRP) therapy has become a promising treatment option in pediatric surgery, offering a novel approach to tissue repair and regeneration. Obtained from the patient’s own blood or umbilical cord blood (CB), PRP is a concentrated form of plasma enriched with platelets, growth factors, and cytokines essential for stimulating tissue healing. This systematic review explores the applications of PRP therapy in pediatric surgical procedures, focusing on its role in promoting wound healing, reducing postoperative complications, and enhancing patient outcomes. A systematic literature overview was conducted in accordance with PRISMA guidelines, encompassing studies published between 2004 and 2024. The research has identified different fields of application for PRP therapy in pediatric surgery, including treatment of pilonidal sinus and hypospadias repair. Key findings from clinical studies and randomized controlled trials are summarized, highlighting the efficacy of PRP therapy in accelerating wound healing, reducing pain, and improving patient recovery. Despite promising results, challenges and controversies surrounding PRP therapy persist, including variability in preparation protocols and optimal dosing regimens. The safety of PRP therapy in pediatric patients is also discussed, emphasizing its autologous nature and minimal risk of adverse reactions. In summary, this review highlights the role of PRP therapy as a safe and effective therapeutic approach in pediatric surgery, while further research to standardize protocols and elucidate optimal treatment strategies are still necessary.

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Clinical study on the role of platelet-rich plasma in human acellular dermal matrix with razor autologous skin graft repair of giant congenital pigmented nevus in children

Cited by 2 publications

References 28 publications

The Application of Blood Products in Plastic Surgery: A Systematic Review

The Application of Blood Products in Plastic Surgery: A Systematic Review

Platelet-Rich Plasma in Pediatric Surgery: A Comprehensive Review

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