clinical study on biochemical profile of neonatal seizures in a medical college hospital

Abstract

Background: Neonatal seizures are one of the most common and distinctive clinical manifestations of dysfunction of neurological system. Neonatal seizures represent non-specific responses of the immature nervous system to varied insults and result in considerable neonatal mortality and long- term morbidity including motor and cognitive disabilities in the childhood. OBJECTIVES: To study the biochemical abnormalities associated with neonatal seizures. To study the clinical presentation, time of onset and its relation to the neonatal seizures in new-born unit. Material & Methods: Study Design: Prospective hospital based observational study. Study area: Dept. of. Paediatrics, Mamata Academy of Medical Sciences, Bachupally, Hyderabad, Telangana. Study Period: June 2021 – May 2022. Study population: All the neonates from birth to 28 days of life satisfying the inclusion and exclusion criteria who got admitted in the Neonatal Intensive Care Unit of Department of Pediatrics. Sample size: study consisted a total of 80 cases. Study tools and Data collection procedure: Written informed consent was taken from the parent or caregivers prior to the enrolment of neonate for the study.