Clinical study of oral mucosal lesions in patients attending dermatology outpatient department in a tertiary care centre

Abstract

<p class="abstract"><strong>Background:</strong> Oral mucosa reflects the general health of an individual. In certain systemic diseases oral cavity may be affected first or it could the only clue to diagnosis. Hence skin examination is never complete without the examination of mucosae. Aims and objectives were to find out the frequency and diversity of oral mucosal lesions in patients attending Dermatology, Venereology and Leprosy (DVL) outpatient department (OPD).</p><p class="abstract"><strong>Methods:</strong> This was a hospital based observational study. All patients with oral mucosal lesions fulfilling the inclusion &exclusion criteria were enrolled in the study. Detailed history, physical examination and clinical photographs were recorded for all the patients.<strong></strong></p><p class="abstract"><strong>Results:</strong> The prevalence oral mucosal lesions among dermatological patients is 1.04% with a female predilection and the mean age was 38.44±17.30. Majority of the patients belonged to the age group of 31-60 years. Established risk factors for developing oral lesions like tobacco and beetle nut use was found in only 24% and 16% of the patients respectively. Twenty% (21%) of the patients were diabetic and the commonest oral lesions in them was oral candidiasis. Eighteen% (18%) of the patients presented with only oral complaints, while 82% of patients came with skin complaints and their oral lesions were incidental findings. Out of 82 patients with dermatological diseases specific mucocutaneous diseases were seen in 44% of patients. Most common dermatological diseases seen were vitiligo, lichen planus and pemphigus vulgaris.</p><p class="abstract"><strong>Conclusions:</strong> Knowing the prevalence of oral lesions as a part of mucocutaneous disorders would help sensitise other specialities the need to examine oral cavity in order to attain appropriate and early diagnosis.</p>

Clinico-Epidemiological Study of Oral Mucosal Lesions in Patients Attending Out-Patient Department in a Tertiary Care Hospital: A Cross-Sectional Study

“…In our study majority number of patients fell into the age group of 21-40 years (60%), with the mean age being 32.03 ± 5.79 years. According to Mandadi et al, Roy et al and Babu et al most patients in their study belonged to the age group 31-40 and the percentages were 25%, 24.67%, and 31.3%, with the mean age being 38.44±17.30 years respectively almost similar to our study [10,6,7]. The predominant involvement of adults could be attributed to the fact that the most common diseases in these studies are seen in adult life.…”

“…In our study among 70 patients, 27 (38.5%) had cutaneous as well as oral manifestations and 43 (61.4%) had just oral manifestations. This is in contrast to the study done by Mandadi, L et al in which among the 100 patients with oral lesions, 82 (82%) of patients had skin manifestations whereas 18 (18%) patients presented with only oral diseases [10].…”

“…Diabetic patients are more susceptible to oral candidiasis due to high levels of salivary glucose, low secretion of saliva, impaired chemotaxis, and defect of phagocytosis due to polymorphonuclear leukocyte deficiency. Mucosal vitilogo was observed in only 2.9% patients in the present study, which was comparatively low as compared to studies done by Mandadi L et al [10] and Shah H et al [14], who found frequency of mucosal vitiligo to be 15.4% and 14.8% respectively.…”

“…In a study by Mandadi L, et al out of 19 oral candidiasis patients 15 (79%) patients had diabetes mellitus (DM) and rest 4 (21%) patients had human immune deficiency virus (HIV) as pre disposing factors for the development of candidal infections [10]. We observed that out of 6 patients with oral candidiasis, 4 patients (66.7%) patients had diabetes mellitus.…”

Oral Manifestations of Patients Diagnosed with Dermatological Diseases: A Cross-Sectional Study in Eastern Province, KSA

“…This study sample presented 16% patients with current smoking status. The prevalence of oral lesions in 15% participants of this this study closely correspond to another study 20 .…”