Clinical study of fibrosing alopecia in a pattern distribution in a Latin American population

Mardones, Francisco; Hott, Karla; Martı́nez, M.C.

doi:10.1111/ijd.13871

Cited by 16 publications

(19 citation statements)

References 5 publications

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“…This entity was described by Zinkernagel and Trüeb in 2000 [18] and has been rarely reported in other epidemiological studies [14,21,24,25] being probably underdiagnosed. In our study, FAPD patients were predominantly females (89%) with a median age of 59 years, which is in concordance with earlier reports (Zinkernagel and Trüeb [18]: 19 patients, 79% females, median age 60 years; Mardones et al [26]: 12 cases, 70% females, median age 48 years). In our opinion, FAPD should be included in future classifications of cicatricial alopecias.…”

Section: Discussionsupporting

confidence: 93%

Frequency of the Types of Alopecia at Twenty-Two Specialist Hair Clinics: A Multicenter Study

Vañó‐Galván

Saceda‐Corralo

Blume-Peytavi

et al. 2019

Skin Appendage Disord

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Background: The frequency of different types of alopecia is not clearly reported in recent studies. Objective: To analyze the frequency of the types of alopecia in patients consulting at specialist hair clinics (SHC) and to assess for global variations. Methods: Multicenter retrospective study including data from patients evaluated at referral SHC in Europe, America, Africa and Australia. Results: A total of 2,835 patients (72.7% females and 27.3% males) with 3,133 diagnoses of alopecia were included (73% were non-cicatricial and 27% were cicatricial alopecias). In all, 57 different types of alopecia were characterized. The most frequent type was androgenetic alopecia (AGA) (37.7%), followed by alopecia areata (AA) (18.2%), telogen effluvium (TE) (11.3%), frontal fibrosing alopecia (FFA) (10.8%), lichen planopilaris (LPP) (7.6%), folliculitis decalvans (FD) (2.8%), discoid lupus (1.9%) Vañó-Galván et al.

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Section: Discussionsupporting

confidence: 93%

Frequency of the Types of Alopecia at Twenty-Two Specialist Hair Clinics: A Multicenter Study

Vañó‐Galván

Saceda‐Corralo

Blume-Peytavi

et al. 2019

Skin Appendage Disord

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“…The authors described patients with FAPD with clinical features of AGA [9] and cicatricial findings, some of them presenting with the involvement of the frontal hair line [1, 12, 13]. Since the original reports, evidence has accumulated that considerable clinical overlap exists between FFA and FAPD, or progression between these conditions, suggesting that FAPD may involve the frontal hairline [1, 3, 4, 12]. A pure form of FFA does not present hair miniaturization associated with a lichenoid perifollicular infiltrate and concentric fibrosis in the same scalp biopsy, but the possibility of the existence of the two entities in the same patient must be considered [2, 4, 14].…”

Section: Discussionmentioning

confidence: 99%

“…Mardones et al [4] were the first to describe the evidence of FAPD amongst Latin Americans in Chile. However, the Chilean population mostly consists of White and Amerindian people so that African patients were not particularly analyzed in that study.…”

Section: Discussionmentioning

confidence: 99%

Fibrosing Alopecia in a Pattern Distribution (FAPD) in 16 African-Descent and Hispanic Female Patients: A Challenging Diagnosis

Teixeira

Dias

Trüeb³

et al. 2019

Skin Appendage Disord

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Background: Fibrosing alopecia in a pattern distribution (FAPD) has only been described in Caucasian patients, and it is not clear whether it can develop in dark-skin ethnicities. Materials and Methods: Sixteen Brazilian female patients, 12 of African descent and 4 Hispanic, with progressive scarring alopecia in a pattern distribution were analyzed. Results: Dermatoscopic features showed perifollicular erythema and scaling (14/16), hair fiber diameter diversity (16/16), loss of follicular ostia (16/16), and follicular keratosis (3/16). Late stages showed a honeycomb pigmented network (12/16), a hyperpigmented perifollicular halo (12/16), and small white patches (12/16). Histopathological features showed lichenoid perifollicular infiltrate (14/16), follicular miniaturization (16/16), concentric fibrosis (16/16), perifollicular lymphocytic infiltrate (16/16), and vellus hair involvement (10/16). Premature desquamation of the inner root sheath was found in 11 patients. Conclusions: The concomitant findings of cicatricial pattern hair loss (with or without the recess of the front hair line), hair fiber diversity, perifollicular erythema and scaling, a whitish perifollicular halo, and histological findings of androgenetic alopecia, with vacuolar interface alteration of the upper portion of the follicular epithelium, are the main key features to suggest the diagnosis of FAPD. FAPD is a possible diagnosis in patients of color with cicatricial pattern hair loss. Clinical, dermatoscopic, and histopathological examination allow a proper final differential diagnosis.

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“…Cases of FAPD have been reported in many regions worldwide [1, 7, 8, 9, 10, 11]. The distinctive histopathologic features of FAPD were miniaturization of hair follicles with prominent lichenoid inflammation and destruction of the follicular basilar epithelium in the isthmus and infundibular region of the follicle.…”

Section: Discussionmentioning

confidence: 99%

Fibrosing Alopecia in a Pattern Distribution: A Case Report and Literature Review

et al. 2019

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Fibrosing alopecia in a pattern distribution (FAPD) is a relatively new entity in the family of cicatricial alopecia. It has been categorized as a member of the lichen planopilaris (LPP) group due to its similarity in clinical and histopathological presentation. Nonetheless, the disease earns its own entity due to its lichenoid inflammation exclusively involving miniaturized hair and area of involvement mimicking pattern hair loss which differentiates itself from other types of LPP or pattern hair loss. Since its first introduction by Zinkernagel and Trüeb in 2000, there have been only few case reports and series of FAPD. We herein report a case of FAPD in a postmenopausal woman who had progressive hair loss over the course of 10 years.

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Clinical study of fibrosing alopecia in a pattern distribution in a Latin American population

Cited by 16 publications

References 5 publications

Frequency of the Types of Alopecia at Twenty-Two Specialist Hair Clinics: A Multicenter Study

Frequency of the Types of Alopecia at Twenty-Two Specialist Hair Clinics: A Multicenter Study

Fibrosing Alopecia in a Pattern Distribution (FAPD) in 16 African-Descent and Hispanic Female Patients: A Challenging Diagnosis

Fibrosing Alopecia in a Pattern Distribution: A Case Report and Literature Review

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