Clinical studies on herbal remedies in children: A systematic literature analysis

Marquardt, P; Kraft, K; Nieber, K

doi:10.1055/s-0034-1394641

Cited by 2 publications

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“…The studies were selected based on the eligibility criteria outlined above. We identified altogether 133 published clinical trials on application of herbal medicinal products that fulfilled the inclusion criteria [11,12]. The data were analysed according to country, the study was performed, age, study design, herb used in the medicinal products and indication.…”

Section: Search Strategies and Data Analysismentioning

confidence: 99%

Clinical trials with herbal medicinal products in children: a literature analysis

Marquardt

Kaft

Nieber

2015

Wien Med Wochenschr

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Herbal medicinal products have been used since several decades for the health care of children. Nevertheless, well-controlled clinical studies with herbal medicinal products for children are rare. The authors' objective therefore was to evaluate clinical trials with herbal medicinal products in children, based on a literature search in PubMed and Web of Science. A total of 133 trials were identified. 90 studies were randomized, 32.2% were randomized and double-blinded. Most studies were performed in China, in the age group 6-12 years, and in children with respiratory diseases, most often herbal medicinal products with Hedera helix were tested. The analysis revealed that studies on herbal medicinal products were feasible in children. Although clinical trials have been found, this literature search have limitations and did not cover all studies performed. However, only few clinical trials of high quality were identified. Further studies therefore are urgently needed to support the good empirical findings.

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Section: Search Strategies and Data Analysismentioning

confidence: 99%

Clinical trials with herbal medicinal products in children: a literature analysis

Marquardt

Kaft

Nieber

2015

Wien Med Wochenschr

View full text Add to dashboard Cite

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Clinical Trial of Herbal Medicine in Children

Belokar¹,

Thakre²,

Kohale³

et al. 2023

IJARSCT

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Herbal medicines have been used for decades to care for children's health. However, well-controlled clinical studies with herbal medicines in children are rare. Therefore, the authors' aim was to evaluate clinical trials with herbal medicines in children, based on literature searches in PubMed and the Web of Science. A total of 133 trials were identified. 90 studies were randomized, 32.2% were randomized and double-blind. Most of the studies were done in China, in the 6-12 age group and in children with respiratory diseases, most of the herbal medicines with Hedera helix were tested. Analysis shows that studies on herbal medicine are feasible in children. Although clinical trials were found, this literature search was limited and did not include all studies performed. However, only a few high-quality clinical trials have been identified. Therefore, further studies are needed to support good experimental results. A total of 133 trials were identified. 90 studies were randomized, 32.2% were randomized and double-blind. Most of the studies were done in China, in the 6-12 age group and in children with respiratory diseases, most of the herbal medicines with Hedera helix were tested. The review found that studies of herbal medicines are feasible in children and also highlights some significant challenges associated with effective monitoring of their safety.

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Clinical studies on herbal remedies in children: A systematic literature analysis

Cited by 2 publications

References 0 publications

Clinical trials with herbal medicinal products in children: a literature analysis

Clinical trials with herbal medicinal products in children: a literature analysis

Clinical Trial of Herbal Medicine in Children

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