Clinical Studies of the Blood Volume. Vi. Changes in Blood Volume in Pernicious Anemia in Relation to the Hematopoietic Response to Intra-Muscular Liver Extract Therapy 1

Clinical Studies of the Blood Volume. Vii. Changes in Blood Volume in Bright's Disease With or Without Edema, Renal Insufficiency, or Congestive Heart Failure, and in Hypertension 1

“…While this relationship is not numerically identical with that found in primary (20) and secondary anemia (21), it is similar in many respects. A distinct difference in respect to total blood volume exists, however, in that in primary anemia, as the red cell count rises to 5 million under liver therapy, the total blood volume increases to normal, whereas in Bright's disease, total blood volume remains below normal regardless of the erythrocyte level.…”

Studies in Cirrhosis of the Liver. I. Relationship Between Plasma Volume, Plasma Protein Concentrations and Total Circulating Proteins

“…Again, the dye failed to appear in the remaining ascitic fluid as long as one hour later under similar conditions. Under cer-IME AND (25). In nearly all instances the patients reported here exhibited at least moderate degrees of anemia and reduced hematocrit values at some time during the course of their study.…”

Clinical Studies of the Blood Volume. Viii. Macrocytic and Hypochromic Anemias Due to Chronic Blood Loss, Hemolysis and Miscellaneous Causes, and Polycythemia Vera 1

“…Since we have found a striking relationship between the severity of anemia and the level of plasma, circulating red cell and total blood volume in pernicious anemia (20) and in Bright's disease (21), it seemed worth while to make a similar study of secondary anemia. The main interest of such a study is to correlate the blood volume level with the clinical course, and in light of these findings to evaluate from a clinical standpoint the common laboratory criteria of anemia: the red cell count, hemoglobin and hematocrit.…”