1972
DOI: 10.1161/01.cir.46.1.5
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Clinical Spectrum of the Sick Sinus Syndrome

Abstract: SUMMARYThe clinical spectrum of the sick sinus syndrome (SSS) is

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Cited by 405 publications
(106 citation statements)
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References 33 publications
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“…However, it is difficult to know whether this combination is the result of the same disease involving both the SA and the AV nodes or the result of 2 different diseases. In contrast to previous reports, 14 in the present study there were no coronary lesions to explain the sclerosis of the SAN or the fatty replacement of the approaches to the AVN. No scattered chronic-inflammatory cells were found in the area.…”
Section: Fatty Infiltrationcontrasting
confidence: 99%
See 1 more Smart Citation
“…However, it is difficult to know whether this combination is the result of the same disease involving both the SA and the AV nodes or the result of 2 different diseases. In contrast to previous reports, 14 in the present study there were no coronary lesions to explain the sclerosis of the SAN or the fatty replacement of the approaches to the AVN. No scattered chronic-inflammatory cells were found in the area.…”
Section: Fatty Infiltrationcontrasting
confidence: 99%
“…All sections were alternately stained with H&E and elastica van Gieson stains as described by Lev. 12 The SAN was unavailable for histopathologic study in 2 cases (cases 8 and 9), the left and right bundle branches were unavailable in 1 case (case 14), and the third portion of the right bundle branch in 2 cases (cases 12 and 13). The percent of SAN cells in relation to fibrous, elastic or fatty tissue was determined under light microscopy.…”
Section: Histopathological Studymentioning
confidence: 99%
“…[8][9][10][11][12][13][14][15][16] Hypertension (78.20%) was the most common associated co-morbidity and 23.07% patients were diabetic, consistent with previous studies. …”
Section: Discussionsupporting
confidence: 83%
“…An association between sinus node dysfunction and atrial tachyarrhythmia has long been recognized. [1][2][3] Elvan, et al in a canine model of pacing-induced chronic AF recognized sinus node remodeling resulting from AF. 7) In this model, the corrected sinus node recovery time and Figure 2.…”
Section: Discussionmentioning
confidence: 99%