Clinical, social and rehabilitation status of long-term home parenteral nutrition patients: results of a European multicentre survey

Gossum, A. Van; Vahedi, Kouroche; Abdel-Malik,; Staun, Michael; Pertkiewicz, M.; Shaffer, Jon; Hébuterne, Xavier; Beau, Philippe; Guédon, Claire; Schmit, Alain; Tjellesen, Lone; Messing, Bernard; Forbes, Alastair

doi:10.1054/clnu.2000.0380

Cited by 93 publications

(36 citation statements)

References 24 publications

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“…Home parenteral nutrition (HPN) has markedly improved the quality of life and the survival of patients with prolonged intestinal failure 1–4 . Lipid emulsions are commonly included in HPN regimens both as part of the energy supply and as a source of essential fatty acids (EFAs; linoleic and α ‐linolenic acids) and fat soluble vitamins.…”

Section: Introductionmentioning

confidence: 99%

Efficacy and safety of an olive oil‐based intravenous fat emulsion in adult patients on home parenteral nutrition

Reimund

Rahmi

Escalin

et al. 2005

Aliment Pharmacol Ther

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SUMMARY Background:The most frequently used intravenous lipid emulsions are composed of 100% long chain triacylglycerols from soybean oil or of 50% long chain triacylglycerols-50% medium chain triacylglycerols. A newer emulsion, ClinOleic 20% containing 80% olive oil and 20% soybean oil, was suggested to reduce lipid peroxidation and immune function impairment. Aim: To assess ClinOleic 20%'s efficacy, safety and effect upon systemic inflammatory parameters in adults on home parenteral nutrition. Methods: In stable home parenteral nutrition patients, the initial intravenous lipid emulsion was changed for ClinOleic 20%. Nutritional status, clinical and biological tolerance, and systemic inflammatory markers were

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Section: Introductionmentioning

confidence: 99%

Efficacy and safety of an olive oil‐based intravenous fat emulsion in adult patients on home parenteral nutrition

Reimund

Rahmi

Escalin

et al. 2005

Aliment Pharmacol Ther

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“…The incidence of CRBSI varies from studies to studies [5-7]. In this study, 44.9% of all patients receiving HPN in the period 2001-2005 had CRBSI.…”

Section: Discussionmentioning

confidence: 73%

Etiology and Epidemiology of Catheter Related Bloodstream Infections in Patients Receiving Home Parenteral Nutrition in a Gastromedical Center at a Tertiary Hospital in Denmark

Nielsen

Chen

Hellesøe³

et al. 2012

TOMICROJ

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We conducted a retrospective epidemiologic study of catheter related bloodstream infections (CRBSI) in patients receiving long-term home parenteral nutrition (HPN) from January 2002 to December 2005. Our results showed that coagulase negative staphylococci (CoNS) were the most prevalent pathogens (44.7% of all CRBSI episodes), followed by Enterobacteriaceae (33.2%). Prevalence for candidemia and Enterococcus bacteremia was relatively high (14.4% and 10.8%, respectively). Cefuroxime resistance was observed in 65.4% CoNS and 31.5% Enterobacteriaceae. Based on the results from the study, a new empiric antimicrobial treatment regiment was suggested.

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“…The main disadvantages of PN are in general the cost and PN-related complications: catheter-related bloodstream infections; liver function abnormalities (e.g. cholestasis); metabolic bone disease; fluid overload, especially in patients with ILD and pulmonary arterial hypertension; electrolyte imbalances; and risk of central vein thrombosis in predisposed patients [136][137][138][139][140]. Moreover, specific problems with PN in SSc are caused by skin involvement, poor quality of veins due to vasculopathy and hand deformities requiring assistance with PN infusion [1].…”

Section: Therapy Of Malnutritionmentioning

confidence: 99%

“…Data on long-term PN in SSc patients are lacking. However, based on studies on PN in patients with chronic intestinal pathology and the data from retrospective studies on PN nutrition in SSc patients, which reported the improvement of quality of life and patients' profit from this therapy, this therapeutic approach is considered as effective in SSc patients [136,[141][142][143][144]. Regular monitoring for complications, control of body weight and adequate altering of nutrient supplements are recommended, along with the establishment of a team for patients' education, prevention of the catheter-related complications and optimising the nutrition intake.…”

Section: Therapy Of Malnutritionmentioning

confidence: 99%

Gastrointestinal Involvement in Systemic Sclerosis: Overview, Neglected Aspects, Malnutrition, Body Composition and Management

Oreská¹,

Tomčík²

2019

New Insights Into Systemic Sclerosis [Working Title]

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Gastrointestinal tract (GIT) involvement is the most common internal organ manifestation and is present in up to 90% of patients with systemic sclerosis (SSc). Clinical manifestations can differ according to the part of the GIT affected, disease course and symptoms. A majority of the symptoms are caused by GIT dysmotility. Up to 8% of SSc patients develop several GIT symptoms, which increase the mortality. Although GIT involvement is rarely the direct cause of death, it can lead to several comorbidities including malnutrition and negative alterations of body composition. These factors have a negative impact on quality of life and increase the mortality. To date, the treatment is rather symptomatic. The pathogenesis of GIT involvement in SSc still remains to be clarified to improve the treatment approaches including intravenous immunoglobulins and microRNA interventions.

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Clinical, social and rehabilitation status of long-term home parenteral nutrition patients: results of a European multicentre survey

Cited by 93 publications

References 24 publications

Efficacy and safety of an olive oil‐based intravenous fat emulsion in adult patients on home parenteral nutrition

Efficacy and safety of an olive oil‐based intravenous fat emulsion in adult patients on home parenteral nutrition

Etiology and Epidemiology of Catheter Related Bloodstream Infections in Patients Receiving Home Parenteral Nutrition in a Gastromedical Center at a Tertiary Hospital in Denmark

Gastrointestinal Involvement in Systemic Sclerosis: Overview, Neglected Aspects, Malnutrition, Body Composition and Management

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