Clinical Significance of Spleen–Remnant Liver Volume Ratio in Hepatocellular Carcinoma Surgery

Abstract

The objective of this study was to explore the value of spleen-remnant liver volume ratio for hepatocellular carcinoma surgery and liver reserve assessment. Spleen-remnant liver volume ratio postoperation was measured with imageological methods and water displacement, and the liver function postoperation and hospital stay of patients with different spleen-remnant liver volume ratios were compared. Spleen-remnant liver volume ratio was closely related to liver function assessment postoperation. The higher the ratio, the higher the assessment score of liver function postoperation would be. When spleen-remnant liver volume ratio was ≤0.9, the patients had a fast recovery and short hospital stay. Spleen-remnant liver volume ratio can effectively predict the recovery and liver reserve of patients with hepatocellular carcinoma postoperation. When postoperative spleen-remnant liver volume ratio is predicted to be ≤0.9, the operation can be performed; and when the ratio is predicted to be ≥1.2, the operation is not suggested.

The impact of hepatic and splenic volumetric assessment in imaging for chronic liver disease: a narrative review

“…For example, using gadoxetic acid liver MRI can provide measurements of liver enhancement, from non-contrast and 20-min delayed post-contrast phases, to assess liver function for the prediction of PHLF [120]. Spleen volume, with and without adjustment to future remnant liver volume, BSA or platelets, has also been correlated with PHLF and survival [121][122][123][124][125][126][127][128][129]. The use of liver and spleen volumetry has also been studied in predicting outcomes following locoregional treatments such as thermal ablation, transarterial chemoembolisation and transarterial radioembolisation and following systemic therapy [130][131][132][133][134][135][136].…”