Clinical significance of nosocomial Cryptococcus laurentii in urine: A case series

Haematologic and Urologic Manifestations of Cryptococcus neoformans

“…neoformans is an environmental basidiomycete fungus that typically causes opportunistic disease in immunosuppressed patients and is most frequently detected in blood, CSF, and respiratory specimens. Cryptococcal species are much less frequently encountered in urinary culture than Candida species [3,7]. In one case study, a cryptococcoma was identifed in a renal transplant patient with persistently culture-negative urine specimens; direct biopsy and culture of the lesion subsequently grew C. neoformans [2].…”

First case report of Cryptococcus laurentii knee infection in a previously healthy patient

“…Human cases of Cryptococcus laurentii infections in various organs and systems have been reported, including Cryptococcus laurentii fungaemia and Cryptococcus laurentii diarrhea in cancer patients [11,12], Cryptococcus laurentii meningitis in HIV patients [13] and other reports of skin and eye infections [14,15].…”

“…Cryptococcus laurentii can be isolated from a wide variety of environments, including air, water, wood, soil, pigeon excreta and many kinds of food [5]. David Chen-Guan Ong et al reported a similar case about a right knee infection of fungus Arthrographis kalrae that was related to a penetration history [11]. The other risk factor was that the patient was treated several times was steroid injections before admission.…”

“…The incidence of infection due to these organisms has increased during the past 40 years, with Cryptococcus laurentii and Cryptococcus albidus being responsible for 80% of all cases of Cryptococcus [5]. Cryptococcus laurentii infections have been reported as central nervous system infections, bloodstream infections, pulmonary infections and infections in other body sites [6][7][8][9][10][11], but a patient with osteoarthritis and a Cryptococcus laurentii infection has not been reported so far. We report a case of fungal arthritis due to Cryptococcus laurentii in an previously healthy patient at our institution.…”

Identification of Yeast and Yeast-Like Fungi at a Tertiary Care Center: A Retrospective Study

“…C. laurentii is rare and commonly seen in immunosuppressed patients. Cutaneous and urinary tract infections were reported in case reports and case series by Molina-Leyva et al [14] and Salazar-Leal et al [15]. All T. asahii were recovered from urine samples taken from patients in the elderly age group.…”