Clinical significance of neck node metastasis in squamous cell carcinoma of the maxillary antrum

Kim, Gwi Eon; Chung, Eun Ji; Lim, John; Keum, Ki Chang; Lee, Sang Wook; Cho, Jaeho; Lee, Chang Geol; Choi, Ahran

doi:10.1016/s0196-0709(99)90078-9

Cited by 53 publications

(14 citation statements)

References 19 publications

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“…Le et al 3 reports an overall incidence of lymph node involvement at diagnosis of 15.5% when only SCC pathology is taken into account. This is consistent with many reports 5,7,9,12,13,23-25 and due to this low number most authors have advocated no elective neck treatment for patients with maxillary sinus carcinoma. However, in the 1990s Paulino et al 7 and Jiang et al 21 began to advocate elective ipsilateral neck irradiation in all patients with SCC due to high incidence of neck relapse associated with SCC histology (28% to 36% in their respective reviews) and the poor prognosis of those who relapsed in the neck 7,21,26 .…”

Section: Elective Management Of the Neck In Maxillary Cancersupporting

confidence: 91%

“…Patients with cervical relapse alone can be salvaged in 50-70% of cases 29 . Local failure is the primary cause of failure in any stage 29 and as such, aggressive therapy to achieve maximum local control of the primary tumor is considered to be more important than elective neck treatment 13 . Thus, based on our own experience, elective treatment of the neck can only be considered justifiable in patients with advanced stage primary carcinomas (T3-4) of the maxillary sinus.…”

Section: Resultsmentioning

confidence: 99%

“…Due to the frequency of local failure, routine neck irradiation was not recommended as the added morbidity of radiation did not overweight the small risk of having isolated neck failure. Kim et al 13 also reported a local failure rate of 68.1% as compared to a regional failure rate of 19% during follow-up (median, 6 years) of their patients.…”

Section: Elective Management Of the Neck In Maxillary Cancermentioning

confidence: 91%

“…This is due to the rich lymphatic pathways of the palate, and therefore they act more as an oral cavity primary rather than maxillary sinus tumor 5,8,13,15,28,29 . In Cantu's 12 series of 156 patients with SCC of the maxillary sinus, 16 patients (10%) had regional recurrence; 11 of which (68.7%) were T2 N0 at presentation.…”

Section: Elective Management Of the Neck In Maxillary Cancermentioning

confidence: 99%

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Management of the neck in maxillary sinus carcinomas

Dooley

Shah²

2015

Current Opinion in Otolaryngology & Head and Neck Surgery

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Purpose of Review To discuss and review the role for elective treatment of the neck in maxillary squamous cell carcinoma. Improvements in survival have been seen due to improved local therapies and control, therefore the treatment of the neck has become a topic of debate. Recent findings The risk of occult metastases in neck nodes is higher for T 3-4 tumors. The rate of nodal relapse in the N0 neck without elective treatment is 8-15%. With elective irradiation the nodal relapse rate decreases. However, most nodal relapses are accompanied by local failure or distant disease. Local failure remains the most common site of failure and cause of death in this patient population. Summary Treatment failure occurs overall in 62% of all patients, with local recurrence by far the most common site of treatment failure which is rarely amenable to salvage therapy. Therefore elective neck irradiation is not routinely indicated in the clinically N0 neck; those who recur only in the neck can be surgically salvaged more than 50% of the time.

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Section: Elective Management Of the Neck In Maxillary Cancersupporting

confidence: 91%

Section: Resultsmentioning

confidence: 99%

Section: Elective Management Of the Neck In Maxillary Cancermentioning

confidence: 91%

Section: Elective Management Of the Neck In Maxillary Cancermentioning

confidence: 99%

See 2 more Smart Citations

Management of the neck in maxillary sinus carcinomas

Dooley

Shah²

2015

Current Opinion in Otolaryngology & Head and Neck Surgery

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“…In patients with maxillary sinus cancer, Kim et al15 reported 13.5% occult metastasis in those who did not receive elective neck dissection at the time of primary resection. Le et al4 described a 5-year nodal relapse rate of 20% in N0 neck of maxillary sinus carcinoma without elective neck control at the time of or after surgery, while this rate was reduced to 0% with elective neck irradiation after surgery.…”

mentioning

confidence: 99%

Is elective neck dissection needed in clinically N0 neck in maxillary cancer?

Park

2014

J Korean Assoc Oral Maxillofac Surg

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Lymph Node Metastases in Malignant Tumors of the Paranasal Sinuses

Cantù¹,

Bimbi²,

Miceli³

et al. 2008

Arch Otolaryngol Head Neck Surg

142

115

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Lymph node metastases are a poor prognostic factor for patients with malignant tumors of the paranasal sinuses. The incidence of these metastases is low, particularly in ethmoid sinus tumors. A prophylactic treatment of the neck in patients with N0 tumors (surgery or radiotherapy) might be considered in T2 squamous cell carcinoma of the maxillary sinus and in undifferentiated carcinoma of the ethmoid sinus.

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Clinical significance of neck node metastasis in squamous cell carcinoma of the maxillary antrum

Cited by 53 publications

References 19 publications

Management of the neck in maxillary sinus carcinomas

Management of the neck in maxillary sinus carcinomas

Is elective neck dissection needed in clinically N0 neck in maxillary cancer?

Lymph Node Metastases in Malignant Tumors of the Paranasal Sinuses

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