“…Several studies have corroborated this finding in lung cancer and other malignant diseases including colorectal cancer, breast cancer, hepatocelluar carcinomas, pancreatic ductal adenocarcinomas and adult T-cell leukemia (Raponi et al, 2009;Greither et al, 2010;Shibuya et al, 2010;Chen et al, 2012;Han et al, 2012;Huang et al, 2012;Ishihara et al, 2012;Papaconstantinou et al, 2012); however, other reports provided insignificant or opposite evidences (Jung et al, 2009;Voortman et al, 2010;Donnem et al, 2011;Saito et al, 2011;Monsálvez et al, 2012;Shinmei et al, 2012). In order to investigate the precise association between miR-155 expression and the prognosis of patients, we combined the HRs extracted from the eligible data, and found that patients with high miR-155 expression were likely to have an unfavorable outcome.…”